氩气预处理通过Toll 样受体介导保护神经元细胞

S Scheid, A Lejarre, J Wollborn, H Buerkle… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
惰性气体氩气在急性损伤后保护神经细胞的作用已得证实, 但氩气预处理的神经保护作用还需要
进一步研究. 实验在用鱼藤酮(20μM, 4h) 诱导人神经母细胞瘤SH-SY5Y 细胞损害之前 …

[HTML][HTML] Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

S Scheid, A Lejarre, J Wollborn, H Buerkle… - Neural regeneration …, 2023 - journals.lww.com
The noble gas argon has the potential to protect neuronal cells from cell death. So far, this
effect has been studied in treatment after acute damage. Preconditioning using argon has …

Neuroprotection (and lack of neuroprotection) afforded by a series of noble gases in an in vitro model of neuronal injury

N Jawad, M Rizvi, J Gu, O Adeyi, G Tao, M Maze… - Neuroscience …, 2009 - Elsevier
Xenon-induced neuroprotection has been well studied both in vivo and in vitro. In this study,
the neuroprotective properties of the other noble gases, namely, krypton, argon, neon and …

[HTML][HTML] Argon: a novel therapeutic option to treat neuronal ischemia and reperfusion injuries?

F Ulbrich, U Goebel - Neural regeneration research, 2015 - journals.lww.com
Neuronal injury and neuroprotection: Ischemia and reperfusion injuries in neuronal cells
such as acute ischemic stroke-represent the third leading cause of death in the world …

[HTML][HTML] Post-stroke treatment with argon preserved neurons and attenuated microglia/macrophage activation long-termly in a rat model of transient middle cerebral …

J Liu, M Veldeman, A Höllig, K Nolte, L Liebenstund… - Scientific reports, 2022 - nature.com
In a previous study from our group, argon has shown to significantly attenuate brain injury,
reduce brain inflammation and enhance M2 microglia/macrophage polarization until 7 days …

[HTML][HTML] Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury

U Goebel, S Scheid, S Spassov… - Neural regeneration …, 2021 - journals.lww.com
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-
like receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and …

[HTML][HTML] Expression analysis following argon treatment in an in vivomodel of transient middle cerebral artery occlusion in rats

AV Fahlenkamp, M Coburn, A de Prada, N Gereitzig… - Medical gas …, 2014 - Springer
Background Argon treatment following experimental neurotrauma has been found
neuroprotective in an array of in vivo and in vitro models. The inherent cellular and …

[HTML][HTML] Argon treatment after experimental subarachnoid hemorrhage: evaluation of microglial activation and neuronal survival as a subanalysis of a randomized …

B Kremer, M Coburn, A Weinandy, K Nolte… - Medical Gas …, 2020 - journals.lww.com
Hereinafter, we evaluate argon's neuroprotective and immunomodulatory properties after
experimental subarachnoid hemorrhage (SAH) examining various localizations …

[HTML][HTML] Argon neuroprotection in ischemic stroke and its underlying mechanism

L Bao, Y Liu, Q Jia, S Chu, H Jiang - Brain Research Bulletin, 2024 - Elsevier
Ischemic stroke (IS), primarily caused by cerebrovascular obstruction, results in severe
neurological deficits and has emerged as a leading cause of death and disability worldwide …

Protective effect of astrocyte-conditioned medium on neurons following hypoxia and mechanical injury

J Yan, T Tan, Q Huang - Chinese Journal of Traumatology, 2013 - mednexus.org
Objective: To investigate the protective effect of mouse astrocyte-conditioned medium (ACM)
on hypoxic and mechanically injured neurons by a cell model in vitro, and to explore the …