Cancer therapy based on gene delivery requires highly efficient molecular delivery methods
into a specific target site. One of the physical methods of gene delivery exploits …

Gene therapy is promising for the treatment of many diseases including cancers and genetic
diseases. From the viewpoint of safety, ultrasound (US)-mediated gene delivery with …

Although gene therapy has great potential as a treatment for diseases, clinical trials are
slowed down by the development of a safe and efficient gene delivery system. In this review …

The regulation of gene expression is a promising therapeutic approach for many intractable
diseases. However, its use in clinical applications requires the efficient delivery of nucleic …

Ultrasound-mediated gene delivery with microbubbles has emerged as an attractive
nonviral vector system for site-specific and noninvasive gene therapy. Ultrasound promotes …

The combination of therapeutic ultrasound (US) and nano/microbubbles is an important
system for establishing a novel and noninvasive gene delivery system. Genes are delivered …

Gene therapy and treatment with siRNA hold potential to treat a wide variety of different
diseases. Genetic material is not usually stable and is generally hydrolyzed following …

Gene therapy is a promising technology for genetic and intractable diseases. Drug delivery
carriers or systems for genes and nucleic acids have been studied to improve transfection …

A Japanese word, monozukuri (literally translated “making things”) is the philosophy of first
having the idea and then the faith in the technical expertise and experience to accomplish …

Micro-and nanobubbles provide a promising non-viral strategy for ultrasound mediated
gene delivery. Microbubbles are spherical gas-filled structures with a mean diameter of 1–8 …