Protection of brain development by antenatal magnesium sulphate for infants born preterm

C Chollat, L Sentilhes, S Marret - Developmental Medicine & …, 2019 - Wiley Online Library
Cerebral palsy (CP) remains the most significant neurological disorder associated with
preterm birth. It disrupts quality of life and places huge cost burdens on society. Antenatal …

Antenatal magnesium sulphate neuroprotection in the preterm infant

S Marret, LW Doyle, CA Crowther… - Seminars in Fetal and …, 2007 - Elsevier
Very preterm infants have high rates of neurological impairments and disabilities. These
rates have not diminished as the survival rates have improved. Basic science research …

[HTML][HTML] Fetal neuroprotection by magnesium sulfate: from translational research to clinical application

C Chollat, L Sentilhes, S Marret - Frontiers in neurology, 2018 - frontiersin.org
Despite improvements in perinatal care, preterm birth still occurs regularly and the
associated brain injury and adverse neurological outcomes remain a persistent challenge …

[HTML][HTML] Magnesium sulfate and fetal neuroprotection: overview of clinical evidence

C Chollat, S Marret - Neural regeneration research, 2018 - journals.lww.com
Antenatal administration of magnesium sulfate is an important part of the neuroprotective
strategy for preterm infants. Strong evidence from five randomized controlled trials and five …

[HTML][HTML] Assessing the neuroprotective benefits for babies of antenatal magnesium sulphate: an individual participant data meta-analysis

CA Crowther, PF Middleton, M Voysey, L Askie… - PLoS …, 2017 - journals.plos.org
Background Babies born preterm are at an increased risk of dying in the first weeks of life,
and those who survive have a higher rate of cerebral palsy (CP) compared with babies born …

Antenatal magnesium sulfate: neuro-protection for preterm infants

S Oddie, DJ Tuffnell, W McGuire - … of Disease in Childhood-Fetal and …, 2015 - fn.bmj.com
The neuro-protective effect of antenatal magnesium sulfate on very preterm infants has been
demonstrated in good-quality randomised controlled trials and meta-analyses. Magnesium …

Effect of magnesium sulfate given for neuroprotection before preterm birth: a randomized controlled trial

CA Crowther, JE Hiller, LW Doyle, RR Haslam - Jama, 2003 - jamanetwork.com
ContextPrenatal magnesium sulfate may reduce the risk of cerebral palsy or death in very
preterm infants. ObjectiveTo determine the effectiveness of magnesium sulfate given for …

[HTML][HTML] Implementation of an antenatal magnesium sulfate protocol for fetal neuroprotection in preterm infants

PE Bouet, S Brun, H Madar, AL Baisson, V Courtay… - Scientific Reports, 2015 - nature.com
The aim of our study was to assess the feasibility of implementing a protocol for the use of
magnesium sulfate to prevent cerebral palsy. This retrospective single-center study included …

[HTML][HTML] A systematic review of magnesium sulfate for perinatal neuroprotection: what have we learnt from the past decade?

R Galinsky, JM Dean, I Lingam, NJ Robertson… - Frontiers in …, 2020 - frontiersin.org
There is an important unmet need to improve long term outcomes of encephalopathy for
preterm and term infants. Meta-analyses of large controlled trials suggest that maternal …

Immediate clinical outcomes in preterm neonates receiving antenatal magnesium for neuroprotection

SK Basu, V Chickajajur, V Lopez, A Bhutada, M Pagala… - 2012 - degruyter.com
Background: Antenatal magnesium sulfate can potentially reduce the risk of cerebral palsy
in neonates delivered between 24 and 32 weeks of gestational age. Some studies using …