口服结肠靶向的纳米递送系统: 原理及设计策略
L Lu, G Chen, Y Qiu, M Li, D Liu, D Hu, X Gu, Z Xiao - Science Bulletin, 2016 - Springer
摘要设计口服结肠靶向的递送系统对于治疗结肠有关的疾病非常重要, 因为这种方式能够使药物
精确施用到病变部位, 提高药物生物利用度和患者的顺应性. 尤其, 以纳米粒子为基础的口服制剂 …
精确施用到病变部位, 提高药物生物利用度和患者的顺应性. 尤其, 以纳米粒子为基础的口服制剂 …
基于炎症环境的口服结肠靶向给药系统研究进展
肖健, 黄仁杰 - 中国现代应用药学, 2017 - zgxdyyyx.ijournals.cn
口服结肠靶向给药系统由于能改善结肠局部疾病的治疗效果和降低不良反应而成为该领域的
研究热点. 口服给药系统设计方法的不断发展显著提高了药物在结肠部位的生物利用度, 然而 …
研究热点. 口服给药系统设计方法的不断发展显著提高了药物在结肠部位的生物利用度, 然而 …
Nanoparticle-based oral delivery systems for colon targeting: principles and design strategies
L Lu, G Chen, Y Qiu, M Li, D Liu, D Hu, X Gu, Z Xiao - Science Bulletin, 2016 - Elsevier
Colon-targeted oral delivery is crucial for the treatment of colon-related diseases, as this
delivery strategy enables precise drug administration to the diseased site, enhances drug …
delivery strategy enables precise drug administration to the diseased site, enhances drug …
Oral nano-delivery systems for colon targeting therapy
T Zhang, G Zhu, B Lu, Q Peng - Pharmaceutical …, 2017 - ingentaconnect.com
Background: Targeting drug delivery is an attractive research area, as it enables localized
treatment, improves the efficacy of therapeutics and reduces systemic toxicity. Colon …
treatment, improves the efficacy of therapeutics and reduces systemic toxicity. Colon …
Advances in colon-targeted nano-drug delivery systems: challenges and solutions
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
Colon Targeted Nano Drug Delivery Systems
H Tarannum, BS Nayak, A Ojha… - Nanoparticle Toxicity and …, 2024 - books.google.com
The colon is the attractive target for the delivery of nano formulation due to distinct
advantages such as near-neutral pH, longer transit time, and reduced enzymatic activity …
advantages such as near-neutral pH, longer transit time, and reduced enzymatic activity …
口服结肠靶向给药系统和制备方法的研究进展
吴庆喜, 姚善泾 - 化工学报, 2013 - hgxb.cip.com.cn
口服结肠靶向给药系统作为第四代药物剂型的发展和应用, 具有靶向定位性,
可提高局部药物浓度, 直接作用于病变部位, 降低药物剂量, 减少副反应等优点 …
可提高局部药物浓度, 直接作用于病变部位, 降低药物剂量, 减少副反应等优点 …
[HTML][HTML] Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue
Colon targeted drug delivery is an active area of research for local diseases affecting the
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …