[HTML][HTML] Interleukin-32 promotes lipid accumulation through inhibition of cholesterol efflux

Z Xu, A Dong, Z Feng, J Li - Experimental and …, 2017 - spandidos-publications.com
Abstract Interleukin-32 (IL-32) is a pro‑inflammatory cytokine and its effects in various
inflammatory diseases have been investigated. However, the role of IL‑32 on …

[HTML][HTML] Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes

MSMA Damen, JC Dos Santos, R Hermsen… - Atherosclerosis, 2018 - Elsevier
Background and aims The role of interleukin (IL-) 32 in inflammatory conditions is well-
established, however, the mechanism behind its role in atherosclerosis remains …

[HTML][HTML] Elevated interleukin-38 level associates with clinical response to atorvastatin in patients with hyperlipidemia

N Yang, Y Song, B Dong, Y Li, L Kou, J Yang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic
disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a …

IL-34 promotes foam cell formation by enhancing CD36 expression through p38 MAPK pathway

Q Liu, J Fan, J Bai, L Peng, T Zhang, L Deng… - Scientific Reports, 2018 - nature.com
Atherosclerosis is characterized as a chronic inflammatory disease and macrophage-
derived foam cells play a central role during the pathologic processes. A newly discovered …

IL-35 improves Treg-mediated immune suppression in atherosclerotic mice

L Tao, J Zhu, Y Chen, Q Wang… - Experimental and …, 2016 - spandidos-publications.com
Abstract Interleukin (IL)-35 is an anti‑inflammatory cytokine that may have a protective role in
atherosclerosis (AS). However, the exact role of IL-35 in the disease, and the etiology of AS …

Interleukin‐32β ameliorates metabolic disorder and liver damage in mice fed high‐fat diet

DH Lee, JE Hong, HM Yun, CJ Hwang, JH Park… - …, 2015 - Wiley Online Library
Objective Chronic excessive food intake leads to energy imbalance, resulting in hepatic
steatosis and inflammation. Interleukin‐32 (IL‐32) is known to be a pro‐inflammatory …

IL-38 in modulating hyperlipidemia and its related cardiovascular diseases

M Lai, H Peng, X Wu, X Chen, B Wang, X Su - International …, 2022 - Elsevier
Hyperlipidemia is confirmed to be associated with several health problems that include the
combination of diabetes mellitus, obesity, and hypertension, ie, metabolic syndrome …

IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1

B Chellan, L Yan, TJ Sontag, CA Reardon… - Journal of lipid …, 2014 - ASBMB
S100A8/9 and S100A12 are emerging biomarkers for disease activity of autoimmune and
cardiovascular diseases. We demonstrated previously that S100A12 accelerates …

IL-33 reduces macrophage foam cell formation

JE McLaren, DR Michael, RC Salter… - The Journal of …, 2010 - journals.aai.org
The development of atherosclerosis, a chronic inflammatory disease characterized by the
formation of arterial fibrotic plaques, has been shown to be reduced by IL-33 in vivo …

IL-33 promotes IL-10 production in macrophages: a role for IL-33 in macrophage foam cell formation

HF Zhang, MX Wu, YQ Lin, SL Xie, TC Huang… - … & molecular medicine, 2017 - nature.com
We evaluated the role of IL-10-in IL-33-mediated cholesterol reduction in macrophage-
derived foam cells (MFCs) and the mechanism by which IL-33 upregulates IL-10. Serum IL …