摘要(中) 於後基因體時代, 表觀基因體學對於生物學家而言是一項重要的研究領域. DNA
甲基化是一種附加到DNA 上的化學修飾, 研究指出發生於CpG 位置上的甲基化狀態與DNA …

DNA methylation is a biochemical modification in epigenetics. The 80% cytosines at CpG
dinucleotide are found methylation. The DNA methylation is important for gene expression …

DNA methylation is known to be associated with cancer susceptibility. Such biochemical
process, however, is also affected by other factors such as age, tissues, nutrition and other …

DNA methylation is an inheritable chemical modification of cytosine, and represents one of
the most important epigenetic events. Computational prediction of the DNA methylation …

DNA methylation (DNAm) occurs at cytosines in CpG dinucleotides and alters gene
expression, and hence it may lead to development of diseases. DNAm is an intermediate …

In mammals, cytosines of most CpG dinucleotides in their genomes except gene promoters
are subject to modification by methyl group (methylation). A number of genes in a mammal …

DNA methylation is an important type of epigenetic modification that plays an instrumental
role in organogenesis, cellular differentiation, suppression of deleterious elements, and …

DNA methylation is known to be associated with cancer susceptibility. Such biochemical
process, however, is also affected by other factors such as age, tissues, nutrition and other …

Motivation The investigation of DNA methylation can shed light on the processes underlying
human well-being and help determine overall human health. However, insufficient coverage …

Background DNA methylation, an important epigenetic mark, is well known for its regulatory
role in gene expression, especially the negative correlation in the promoter region …