[HTML][HTML] 血管內皮細胞在腫瘤微環境中促進透明腎細胞癌形成之研究

HH Nguyen-Tran - 2021 - ir.lib.ncu.edu.tw
摘要(中) 腎細胞癌(Renal cell carcinoma, RCC) 是十大癌症之一, 占腎癌的90% 以上. 其中,
透明腎細胞癌(clear-cell RCC, ccRCC) 是最為常見的一種形態, 占所有RCC 病例的75% 以上 …

[HTML][HTML] Study of the Interaction between VHL/Vhlh Deficient Kidney Epithelial Cells and Macrophages—Relevance to the Development of Clear-Cell Renal Cell …

TN Nguyen - 2022 - ir.lib.ncu.edu.tw
摘要 (中) 腎細胞癌 (renal cell carcinoma) 由腎小管上皮細胞惡化而來, 佔 90%
的腎臟惡性腫瘤, 其中又以腎透明細胞癌 (clear-cell renal cell carcinoma, ccRCC) 類型最多 …

Abstract B031: Effect of macrophage inflammatory response and VHL mutation status on the development of clear cell renal carcinoma

CY Kuo - Cancer Research, 2023 - AACR
Kidney [A1] cancer is a serious health care issue problem around the worldworldwide. It is
symptomless asymptomatic in the early stage and is refractory to most [A2] of the cancer …

The VHL-HIF signaling in renal cell carcinoma: Promises and pitfalls

C Morais, DW Johnson, GC Gobe - Emerging Research and …, 2012 - books.google.com
Renal cell carcinoma (RCC) is the third most common genitourinary cancer behind prostate
and bladder cancer, accounting for 3% of all adult malignancies (Curti, 2004). It is a highly …

Diverse regulation of HIF-1 on VEGF in renal cell carcinoma

CB Beleslin, S Damjanovic, RS Bizic… - Endocrine …, 2020 - endocrine-abstracts.org
The clear cell renal cell carcinoma (ccRCC) can be sporadic or familiar, with the mutated
von Hippel-Lindau (VHL) gene. The inactive VHL protein prevents degradation of hypoxia …

Downstream targets of VHL/HIF-α signaling in renal clear cell carcinoma progression: mechanisms and therapeutic relevance

S Mazumder, PJ Higgins, R Samarakoon - Cancers, 2023 - mdpi.com
Simple Summary Clear cell renal cell carcinoma (ccRCC) progression, which is the most
common form of kidney cancer, is associated with the loss of the Von Hippel-Lindau (VHL) …

Different angiogenic potential in low and high grade sporadic clear cell renal cell carcinoma is not related to alterations in the von Hippel–Lindau gene

MM Baldewijns, IJH van Vlodrop… - Analytical Cellular …, 2009 - content.iospress.com
Background: von Hippel–Lindau (VHL) inactivation is common in sporadic clear cell renal
cell carcinomas (ccRCC). pVHL is part of the ubiquitin ligase complex that targets the alpha …

Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue

HH Nguyen-Tran, TN Nguyen, CY Chen, T Hsu - Cancer research, 2021 - AACR
Clear-cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell
carcinoma (RCC), and its progression has been linked to chronic inflammation. About 70 …

Somatic VHL alteration and its impact on prognosis in patients with clear cell renal cell carcinoma

JH Kim, CW Jung, YH Cho, J Lee… - Oncology …, 2005 - spandidos-publications.com
Somatic inactivation of the von Hippel-Lindau (VHL) gene is the most frequent genetic event
observed in clear cell renal cell carcinoma (CC-RCC). However, the prognostic relevance of …

VHL Deficiency and the Tumor Microenvironment in Renal Cell Carcinoma

MM Wolf - 2024 - ir.vanderbilt.edu
Clear cell renal cell carcinoma (ccRCC) is characterized by dysregulated hypoxia signaling
and a tumor microenvironment (TME) highly enriched in myeloid and lymphoid cells. Loss of …