热应激对奶牛GNAS 启动子区DNA 甲基化水平的影响

陈玉梅, 张聪聪, 胡丽蓉, 房浩, 窦金焕, 郭刚… - 中国农业 …, 2023 - chinaagrisci.com
DNA methylation is an important epigenetic regulatory mechanism involved … DNA methylation
related to heat stress in dairy cows and to identify target genes related to DNA methylation, …

表观基因组治疗神经变性

F Coppedè - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… the primary DNA sequence, and include DNA methylation and … been proposed as potential
therapeutic targets to treat or delay … on targeting the epigenome to treat neurodegeneration. …

DNA 甲基转移酶1 调节神经元的存活

J Symmank, G Zimmer - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
DNA methylation and histone modifications are involved in the regulation of neuronal
development, function and aging. DNA methylation by DNA … To approach potential target genes of …

表观基因组可成为帕金森病的治疗标靶?

SV Hegarty, AM Sullivan, GW O'Keeffe - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
DNA methylation (Figure 1). This refers to the covalent methylation of residues in CpG
dinucleotides within the DNA … modulators, such as those targeting DNMTs, HDACs and HATs, hold …

高温影响拟南芥减数分裂染色质上5-甲基胞嘧啶的分布.

刘虹, 杨珂, 宁莹洁, 马月平, 宋粲… - Journal of South …, 2023 - search.ebscohost.com
… DSBs and COs are shaped by DNA methylation status of the chromatin. … modifications
especially for DNA methylation of the … of DNA and histone proteins [2,4,15,17],which are targets of …

表观遗传干预大脑年轻化: 锚定年龄相关的转座子

A Sfera, L Fayard, C Osorio, A Price - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
targets excessive DNA demethylase, methyl groups-removing enzymes, fine-tuning the
genomic and mtDNA methylation … Folate as an epi-vitamin: Folate is crucial for DNA methylation

活动依赖性的基因组结构重塑在印记细胞中促进记忆的形成和回忆

A Marco - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
DNA accessibility. Generally, when chromatin is tightly packed or the DNA is blocked by methyl
molecules (ie, DNA methylation… of distance and orientation to their target genes, and they …

人干细胞来源的小胶质细胞将成为阿尔茨海默病研究必不可少的工具箱

T Liu - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
manipulate the epigenome status to induce aging in the hMGL cell (my unpublished data).
DNA methylation … : a DNA binding domain, allowing proteins to precisely target on specific …

利用斑馬魚模式針對與因葉酸缺乏所引起之胚胎神經管缺陷的相關基因進行基因體及後基因體學之研究(I)

傅子芳 - 2012 - nckur.lib.ncku.edu.tw
… intracellular methylation potential, alter DNAmethylation pattern … for developmental research,
target identification, diseases … The DNA methylation profiles will also be characterized. In …

探索阿尔茨海默病神经表观基因组: 最新进展和未来趋势

H Zhang, F Elefant - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
DNA modifications are DNA methylation and demethylation at the 5-position of the cytosine,
and the link between global DNA methylation … help identify specific therapeutic targets for a …