… that target transforming growth factor-β (TGFβ) signalling … TGFβ signalling pathway is a
drug target, the potential clinical applications of TGFβ inhibition, the issues arising with anti-TGFβ …

… that overactivation of TGF-β signalling might contribute to later … For these reasons, targeting
the TGF-β signalling pathway is … -the-art in the signalling pathways induced by TGF-β that are …

Trans forming growth factor β(TGF-β) and related cytokines regulate cell fate by signalling …
lets us, for the first time, trace a signalling pathway from TGF-β receptors to target genes. …

… Deregulation of TGFβ expression or signalling has been implicated in the pathogenesis of a
… most common genetic event affecting the TGF-β signalling pathway and occurs in approx. 20…

… The SMAD signalling pathway is a central 'conduit' for all these gene responses and, as such,
it … The context more than the proteins involved in the signalling pathway is what shapes the …

… The regulation of Smad1 and Smad2 phosphorylation by BMP and TGF-ß/activin signalling
pathways, respectively, is thightly regulated. Recent studies have revealed that MADR …

… within the signalling network are currently in the centre of TGF-β signal transduction research
and … The two parallel signalling pathways of TGF-β1 in endothelial cells, mediated by either …

… This review discusses the TGF-β signalling pathway, its … TGF-β signalling is also essential
for embryonic development, … Alterations of the TGF-β signalling pathway are involved in human …

… and Smad2 act together in activin and TGF-B signalling pathways in breast epithelial cells. …
in distinct TGF-ß signalling pathways (Fig. 5). The entire SMAD signalling network may …

… Among the large number of signaling molecules, the transforming growth factor β (TGF-β)
family is highly conserved in the animal kingdom, and is thought to have appeared from the …