… The 3xTg-AD mice progressively develop Aβ and tau patholo… level of the 3xTg AD mice at
10 months of age. Treatment of … did not show any alteration in NeuN immunoreactivity. The …

… extracellular deposition of amyloid beta (Aβ), the formation of … -old transgenic mouse model
of AD (3xTgAD) has shown … covalent modifications without altering the DNA sequence. They …

… Investigators increasingly show that long-term PM2.5 … exceed the US EPA standard level
long-term, Aβ and brain-derived … GCs are a suspected link between chronic stress and altered …

… with increased Aβ accumulation in that study. Altered proteostasis caused by increased
sleep … One study found that AD mice exhibited sleep disorders in which wakefulness was …

… ROS induced by lipopolysaccharide, Aβ, and other proteins, … Alcohol-treated traumatic brain
injury mice exhibit increased … , neurodegeneration, and behavior: What we can learn from …

… Indeed, we recently found that although Aβ deposition was … neuronal cultures with Aβ
oligomers, increased levels of IRS-… : insights from imaging and behavioral studies. Ageing Res …

… species increase that promotes a redox imbalance. In contrast, the oxidative stress could have
… Dosing paradigm for neurotrophic factor intrathecal administration was changed after the …

… 然大量研究支持Aβ 位于Tau 上游的假说,并认为 Aβ可能触发或… 月龄3xTg-AD 小鼠与同月 龄
C57BL/6对照小鼠相比,在旷场实验… Expression of phosphodiesterase 4 is altered in the brains of …

… and behavioral disorder due to the progressive loss of normal … 减少APP 被降解成Aβ的生理
过程,进而降低脑内Aβ水平,这 一尝试… disease-like pathology in the 3xTg-AD mouse model[J]. J …

… Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance.
Proceedings of the National Academy of Sciences of the United States of America, 107(9)…