糖尿病的发育起源: 环境表观基因组学和新模式

H Zhu, G Ding, X Liu, H Huang - Journal of Diabetes, 2023 - search.proquest.com
… with abnormal Igf2/H19 DNA methylation modification in off… diabetes model, it remains
unknown what are the initiating … Aberrant DNA methylation of imprinted loci in superovulated …

[HTML][HTML] 寻常型银屑病外周血单个核细胞和皮损组织表观遗传修饰异常的研究

苏玉文 - 2010 - cgl.org.cn
… , we detected DNA methylation status, histone acetylation/methylation levels and microRNAs
… Conclusion Aberrant DNA methylation may play an important role in the pathogenesis of …

[PDF][PDF] 盛 6

M Ninomiya - Jpn J Cancer Res, 2001 - mhlw-grants.niph.go.jp
… the aberrant transcription repression on many target genes can be … Wong, Nmediates DNA
methylation-dependent repression … ), is a common cytogenetic abnormality in various myeloid …

利用基因组数据挖掘对人类长非编码RNA 进行功能注释

BL Gudenas, J Wang, S Kuang, A Wei… - Journal of Zhejiang …, 2019 - Springer
… epigenetic modifications such as DNA methylation, histone … lncRNA subcellular localization
are mostly unknown. A … : the (epi)genetics of neurodevelopmental disorders in the era of …

诱导多能干细胞来源的神经细胞模型的应用

CE McKinney - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… and neurodevelopmental disorders are … disorders may require a human neuronal cellular
model that is able to recapitulate the genetic causes of the pathology and to produce the target

解码表观遗传密码: 探索脊髓损伤恢复的新领域

BY Zhang, PY Chang, QS Zhu, YH Zhu - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… , the DNMT up-regulation induced aberrant DNA methylation in motor neurons; this may indicate
a … Certain RAGs, such as Atf3, which were previously blocked by DNA methylation, were …

MicroRNAs 作为颞叶癫痫和颞叶内侧癫痫的潜在生物标志物

B Martinez, PV Peplow - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… is the most common childhood neurological disorder and, … DNA methylation profiles were
constructed primarily focusing … Aberrantly methylated miRNAs and lncRNAs are related to …

[PDF][PDF] 神经认知障碍临床人群中RNA 修饰系统的失调

HM Knight, MD Öz… - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
methylation systems contribute to neurocognitive disorders. … in these compartments are still
relatively unknown. Similarly, … However, the contrasting aberrant patterns identified across …

超氧化物歧化酶1-肌萎缩侧索硬化症的认知障碍

I Martinelli, E Zucchi, C Simonini… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… across genes, which is important for the therapeutic strategy targeting genetic mutations. …
, including environment and other unidentified agents including modifier genes. Key Words: …

微小RNA 作为诊断精神分裂症的潜在生物标志物及抗精神病药物治疗的影响

B Martinez, PV Peplow - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… Although the association between aberrant miRNA expression … disorders (SZ, bipolar
disorder, major depression disorder) … Other epigenetic mechanisms such as DNA methylation