… called Lewy bodies, which contain high levels of aggregated α-… Parkinson disease risk
locus is associated with GAK … alpha-synuclein aggregation in dementia with Lewy bodies, …

… , characterized by aggregation of the protein alpha-Synuclein (… (PD), multiple system atrophy
(MSA) and dementia with Lewy … monoclonal antibody, in patients with Parkinson disease: A …

… disorders, including dementia with Lewy bodies and rapid eye movements sleep behavior
disorders (… D domain mutations in PD alpha-synuclein aggregation and loss of dopaminergic …

… -causing proteins are associated with multiple diseases. For … alpha-synuclein forms toxic
aggregates in multiple diseases including Parkinson’s disease, dementia with Lewy bodies, …

… alpha-synuclein/total alpha-synuclein ratio in Parkinson’s … Lewy aggregates contain amyloid
fibrils of full-length monomeric … seeding activity as a novel biomarker for Parkinson disease. …

… The misfolding and aggregation of α-synuclein is the general … , such as Parkinson’s
disease, dementia with Lewy bodies, and … alpha-synuclein to Lewy body and Lewy neurite-like …

… formation of Lewy bodies, which consists primarily of alpha-synuclein aggregates. However,
… from Parkinson’s disease and dementia with lewy bodies. Proc Natl Acad Sci USA 95:6469-…

… neuronal cytoplasmic inclusions called Lewy bodies (LB) or Lewy neurites, which consist
of the abundant presynaptic protein alphasynuclein (α-syn) in an aggregated form. Apart from …

… : Implications in Parkinson’s disease pathogenesis [J]. BBA-Proteins … Aggregation of
alpha-synuclein in Lewy bodies of sporadic Parkinson’ s disease and dementia with Lewy bodies [J]…

… a major component of Lewy bodies and Lewy neurites, which … with progression of dementia
at advanced disease stages. It … for aggregation and cellular properties of alpha-synuclein. J …