阿尔茨海默病中β 淀粉样蛋白与脑毛细血管内皮细胞的关系

YL Zhang, J Wang, ZN Zhang, Q Su… - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… between amyloid-beta and brain capillary endothelial cells in Alzheimer’s disease. Neural
… migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1…

他汀类药物对β 淀粉样蛋白诱导的神经毒性的神经保护作用

HH Li, CL Lin, CN Huang - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… the amyloid β (Aβ) levels by affecting amyloid precursor … in endothelial cells Simvastatin
in brain capillary endothelial … stress, mitochondria dysfunction and neuronal cell apoptosis. …

星形胶质细胞在阿尔茨海默病β 淀粉样蛋白损伤后血脑屏障破坏中的新作用

Q Yue, MPM Hoi - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
brain endothelial cells in the presence of amyloid pathology. … molecules, mitochondrial
dysfunction, overproduction of ROS … correlates with astrogliosis in oligomeric amyloid β-treated …

低氧诱导因子1 病毒载体可抑制海马神经元的凋亡

X Chai, W Kong, L Liu, W Yu, Z Zhang… - 中国神经再生研究(英文版), 2014 - sjzsyj.com.cn
… The characteristic neuropathology of Alzheimer’s disease includes senile plaques … Second,
amyloid-beta peptide-dependent oxidative damage induces mitochondrial dysfunction, a …

淀粉样蛋白β 和tau 蛋白超越阿尔茨海默病

M Abyadeh, V Gupta, JA Paulo… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… affects brain endothelial cells and the integrity of the brain’s … Aβ-induced mitochondrial ROS
were shown to be involved in … amyloid β in axons of long-term survivors of traumatic brain

痴呆症中的胰腺参与者: 胰岛淀粉样多肽在大脑中积聚的病理作用

AS Bortoletto, RJ Parchem - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… these involves the increased secretion of amylin, or islet amyloid … IAPP has also been shown
to cause mitochondrial dysfunction … amyloidogenic proteins function as seeds in amyloid β-…

改变的O-GlcNAcylation 和线粒体功能障碍, 脑葡萄糖失调和散发性阿尔茨海默病之间的分子联系

CW Huang, NC Rust, HF Wu, GW Hart - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… Specifically, we discuss the molecular roles of O-GlcNAcylation and mitochondrial dysfunction
… O-GlcNAcylation and mitochondrial dysfunction are likely involved in the early phases of …

金丝桃苷可保护血脑屏障免受Aβ1-42 的神经毒性

CY Liu, K Bai, XH Liu, LM Zhang, GR Yu - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… Mounting evidence indicates that amyloid β protein (Aβ) … -3, a downstream effector involved
in the execution of apoptotic … Aβ1–42-induced brain endothelial cell damage by effectively …

神经血管单元的片上生理模拟: 挑战与展望

SI Ahn, YT Kim - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
brain microenvironment. In general, brain endothelial cells are cultured to form a tight brain
… alpha-synuclein accumulation, mitochondrial dysfunction, and neuronal death, have been …

支链氨基酸代谢在阿尔茨海默病和其他代谢紊乱的发展中的作用

B Polis, AO Samson - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… The BCAT family consists of two isoforms, mitochondrial BCATm and cytosolic BCATc. …
amino acids (BCAAs) transport to the brain via the luminal membrane of an endothelial cell. …