[PDF][PDF] Minimal residual disease monitoring in chronic myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation using interphase …

HQ Zhu, XL Liu, LL Song, QF Liu, FY Meng… - … J Cancer, 2010 - scholar.archive.org
… Although the emergence of imatinib has pioneered on the targeting treatment for CML, …
detection revealed a ratio of BCRABL to ABL of 0.18, which were far from complete molecular

间充质干细胞逆转白血病K562 细胞伊马替尼耐药性的研究

孙静 - 2018 - ir.lzu.edu.cn
… for molecular targeted therapy of chronic myelogenous leukemiaDetection of drug resistance
of leukemia cells co-culture with … RT-PCR was used to detect the drug resistance of K562/R …

[PDF][PDF] PESV 对K562 细胞BCR/ABL 融合基因及凋亡调控因子Bcl-2, Bad 表达的影响

于文俊, 杨文华, 杨向东, 史哲新, 王兴丽… - 现代生物医学 …, 2012 - biomed.cnjournals.com
… fluorescence quantitative RT-PCR detection of BCR / ABL, Bcl-… 组应用荧光定量RT- PCR 检测
BCR/ABL 融合基 因,其变异系数(… in patients with chronic myeloid leukemia; role of BCR/ABL, …

慢性髓细胞白血病对伊马替尼产生耐药性的机制

夏君燕, 朱平 - World Journal of Cancer Research, 2012 - hanspub.org
… Abstract: Chronic myeloid leukemia is a clonal … This translocation generates a fusion
protein, BCR-ABL which has … Imatinib is an artificial design targeted drug of tyrosine kinase …

miRNA-196b 过表达对K562 细胞增殖, 凋亡及survivin, Cox-2 表达的影响

尹虹, 刘玥, 郑文岭, 宋艳斌, 马文丽 - 中国癌症杂志, 2014 - china-oncology.com
… were measured by CCK-8 assay and Annexin V-PE, … as a therapeutic target for chronic
myelogenous leukemia. [Key … 过采用PCR扩增长度为284 bp 的pre-miR-196b 扩增片段,PCR产物…

[PDF][PDF] 慢性粒细胞白血病耐药机制及治疗策略

刘旭军, 周晋, 赵艳红, 杨昆鹏, 侯宇航 - 现代生物医学进展, 2014 - biomed.cnjournals.com
… 时实时定量PCR 阳性代表复发危险度升高(42%: 3%),PCR 阴性者… ABL kinase inhibitors to
target unmutated BCR-ABL and BCR… of bcr-abl molecular detection in chronic myeloid leukemia

[HTML][HTML] BCR-ABL 突变检测指导下的达沙替尼治疗伊马替尼耐药的慢性髓性白血病疗效分析

江倩, 秦亚溱, 赖悦云, 江浩, 石红霞 - Chinese Journal of …, 2016 - ncbi.nlm.nih.gov
… based on BCR-ABL mutation detection in imatinib-resistant patients with chronic myeloid
leukemia … 3.分子学:实时定量PCR法检测BCR-ABL转录本水平,采用外周血或骨髓标本,以…

[HTML][HTML] T315I 基因突变的慢性髓性白血病临床特征及泊那替尼疗效

陈晨, 许娜, 江雪杰, 吴婉儿, 周璇, 刘靓… - Journal of Southern …, 2019 - ncbi.nlm.nih.gov
… To analyze the clinical features of chronic myeloid leukemia (CML) … were detected by
examination of BCR-ABL kinase domain (… 测序仪对PCR产物进行测序,检测BCR-ABL KD突变情况…

[HTML][HTML] CRISPR/Cas9 介导的microRNA-21 敲除对慢性髓性白血病细胞伊马替尼敏感性的影响

张雲, 王凌燕, 李佳蒸, 江佩芳, 胡建达… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
… obtained by genomic DNA PCR screening, Sanger sequencing, and real-time PCR. We
used … cell proliferation, and determined imatinib sensitivity by MTT assay and Annexin-Ⅴ-APC/7-…

伊马替尼一线治疗慢性粒细胞白血病慢性期患者-单中心十年回顾性分析

李菲, 张晓洁, 张荣艳, 肖承京, 卢炜, 饶佳, 周玉兰… - 中国肿瘤临床, 2016 - cjco.cn
BCR-ABL 融合基因或逆转录 PCR定性或定量检测BCR-ABLmolecular remission,CMoR)定义
为未检测到BCRABL转录本,… of transplantation for chronic myeloid leukemia: what have we …