[PDF][PDF] Germ-line epimutations and human cancer

PY Wu, YM Fan, YP Wang - Ai Zheng, 2009 - scholar.archive.org
… of heritable gene expression which are not related to DNA sequence changes. Epigenetic
mechanisms play an important role in tissuespecific gene expression during differentiation, …

[PDF][PDF] Main cellular components and their combination models of stem cell niches

J Zhang - Advances in Clinical Medicine, 2018 - researchgate.net
… Long-term cumulative effects can lead to great changes in the microenvironment surrounding
stem cell niche b. When some committed stem cells @ for constructing stem cell niche a …

Soluble epoxide hydrolase: a potential target for metabolic diseases: 可溶性表氧化物酶: 代谢性疾病的潜在治疗靶点

J He, C Wang, Y Zhu, D Ai - Journal of diabetes, 2016 - Wiley Online Library
effects on high-carbohydrate and high-fat diet-induced … -term, high-fat diet induced the
expression of sEH in mouse … or deficiency ameliorated high-fat diet-induced fatty liver disease.9 In …

通过饮食多酚进行表观遗传修饰和肿瘤化学预防

A GOEL - 中国药理学与毒理学杂志, 2015 - cjpt.magtechjournal.com
… Thispresentation will describe some of the current scientific evidence for the role of epigenetic
alterations induced by curcumin and boswelliaꎬ in support of their anti-cancer activitiesꎬ …

茶多酚干预神经退行疾病: 确实有效吗?

HM Hügel, N Jackson - 中国神经再生研究(英文版), 2015 - sjzsyj.com.cn
… For example, by stimulating lipid metabolism in rats, the green tea flavanol epigallocatechin
gallate (EGCG) reversed the high-fat diet induced hypercholesterolemic levels in rats and …

Macro‐and microvascular endothelial dysfunction in diabetes: 糖尿病诱导的内皮细胞功能损伤

Y Shi, PM Vanhoutte - Journal of diabetes, 2017 - Wiley Online Library
… types of epigenetic effects.176 We are not aware of studies specifically examining epigenetic
… Indeed, most studies involving epigenetic changes in diabetes collect samples (serum, …

重新思考神经退行性疾病: 将脂质氧化与中枢神经系统疾病联系起来的神经代谢概念

SS Helgudóttir, AS Mørkholt, J Lichota… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… In this section, we discuss the concepts surrounding the targeting of CPT1A and its implications
for lipid metabolism in both physiological and pathological contexts. In the framework of …

[HTML][HTML] 肠道菌群及其代谢产物与T2DM发病机制及干预措施*

甘巧, 孟庆雄 - 中国生物工程杂志, 2022 - manu60.magtech.com.cn
Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with
reduced folate levels. The Journal of Clinical Endocrinology & Metabolism, 2015, 100(11):E1491-…

草甘膦作为促炎信号传导和认知障碍的直接或间接激活剂

Y Izumi, KA O'Dell, CF Zorumski - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… are several possible measures to control dysbiosis and neuroinflammation caused by
glyphosate. Dietary intake of polyphenols, such as quercetin, which overcome the inhibitory effect

[HTML][HTML] Efficacy of Ganshuang granules (肝爽颗粒) on non-alcoholic fatty liver and underlying mechanism: a network pharmacology and experimental verification

ZHI Guoguo, S Bingjie, T Zheng… - Journal of Traditional …, 2024 - ncbi.nlm.nih.gov
… Then, the mouse models of NAFLD were constructed in a diet-induced manner and
treated with GSG. The levels of interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α) and …