[HTML][HTML] 利用CRISPR/Cas9 基因编辑靶向下调FGFR2 缓解Apert 综合征小鼠颅缝早闭

罗凤涛, 谢杨丽, 李灿, 谭乔燕, 杜晓兰, 陈林 - 生物医学转化, 2021 - swyxzh.ijournals.cn
… ) specifically targeting the Fgfr2 gene was screened and … basis of gene therapy for Apert
syndrome, and is prospective to provide new strategies for the treatment of skeletal genetic

生理和病理条件下脑中SOX 转录因子和microRNA 的相互作用

M Stevanovic, DS Ninkovic, M Mojsin… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
Therapeutic strategies that target SOX/microRNA interplay have emerged in recent years
as a promising tool to target neural tissue regeneration and enhance neurorestoration. …

[HTML][HTML] 成纤维细胞生长因子8 调控骨发育和稳态的研究进展

宏灿黄, 洁雅魏, 德茂张, 学东周 - Journal of Sichuan University …, 2022 - ncbi.nlm.nih.gov
… , such as Kashin-Beck disease, craniosynostosis, cleft palate and osteoarthritis, severely …
in bone development and may become a potential therapeutic target. Herein, we reviewed the …

Noggin 在脊髓损伤中的神经保护作用

N Al-Sammarraie, M Mahmood, SK Ray - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… So, the neuroprotective role of Noggin in SCI warrants further preclinical investigations to
make it translational to the clinics and to determine whether it is a potential therapy to improve …

尼尔样1 型生长因子通过促进软骨生成及抗炎作用来治疗骨关节炎的潜力

唐小凯, 李伟明 - 中国组织工程研究, 2021 - cjter.com
… to genetic engineering and tissue construction. The ultimate goal of an effective treatment
However, Nell-1 has a great potential in the treatment of osteoarthritis as a result of its dual …

大脑新皮质投射神经元正常发育及其功能异常相关的转录调控机制

N Wang, R Wan, K Tang - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… the relationship between gene and lineages of cortical projection neuron were included.
A combination of the following text words was used in the section of “Gene dysfunction and …

尼尔样1 型生长因子促进修复骨再生和治疗骨质疏松的应用潜力

曹曦, 崔伟, 陈跃平, 冯洋, 路通 - 中国组织工程研究, 2019 - cjter.com
… RESULTS AND CONCLUSION: Nell-1 was firstly found to be associated with craniosynostosis
and later has been proved to be an effective bone growth factor. Nell-1 possesses the …

脱钙骨基质体外诱导骨髓间充质干细胞的成骨分化

陈俊毅, 王宁, 陈西淼, 朱伦井, 段江涛, 张贤平… - 中国组织工程研究, 2021 - cjter.com
… Cell-based and future therapeutic strategies for femoral head necrosis. Orthopade. 2018;47(…
Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb …