组蛋白去乙酰化酶抑制剂与肾脏疾病
杜晓艳, 冯宇颖, 马良, 付平 - 中华肾病研究电子杂志, 2019 - zhsbyjdzzz.cma-cmc.com.cn
… deacetylation is one of the important ways of epigenetic modification of histones. … Inhibition
of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in …
of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in …
p300/CBP 在肾脏纤维化的作用和机制
王艳哲, 吴明, 叶朝阳 - 肾脏病与透析肾移植杂志, 2022 - njcndt.com
… epigenetic modification was tightly associated with the occurrence and development of renal
fibrosis… p300 mediates the histone acetylation of ORMDL3 to affect airway inflammation and …
fibrosis… p300 mediates the histone acetylation of ORMDL3 to affect airway inflammation and …
组蛋白修饰与糖尿病肾病
曹子彧, 马东红 - 临床肾脏病杂志, 2022 - lcszb.com
… ,the role of histone modification in the pathogenesis of DN … 酶(histone acetyltransferase,HAT)和
去乙酰化酶(histone deacetylase,… Trichostatin A ameliorates renal tubulointerstitial fibrosis …
去乙酰化酶(histone deacetylase,… Trichostatin A ameliorates renal tubulointerstitial fibrosis …
糖尿病肾病中的组蛋白修饰与靶向干预的研究进展
姜梦迪, 张文 - 上海交通大学学报(医学版), 2021 - xuebao.shsmu.edu.cn
… As important parts of it, histone acetylation, methylation, … This article reviews progresses
of the histone modification and … mediated macrophage infiltration and renal fibrosis in type 2 …
of the histone modification and … mediated macrophage infiltration and renal fibrosis in type 2 …
[HTML][HTML] 组蛋白修饰在急性肾损伤向慢性肾脏病转化中的作用
淑娴郭, 择阳张, 晋赵, 进国袁… - Journal of Sichuan …, 2023 - ncbi.nlm.nih.gov
… Histones are basic proteins that intricately bind the DNA in chromosomes. After … , histones
undergo various modifications on their amino-terminal tails, such as methylation, acetylation, …
undergo various modifications on their amino-terminal tails, such as methylation, acetylation, …
[PDF][PDF] 组蛋白乙酰化修饰对系膜细胞内纤溶酶原激活物抑制物1 基因表达的影响
刘念, 崔英春, 孙广东, 远航, 罗萍, 苗里宁 - 中华肾脏病杂志, 2012 - cjn.org.cn
… Effect of histone acetylate modification on the plasminogen … To investigate the effect of
histone acetylation change on the … renal fibrosis in diabetes. Am J Nephrol, 2009, 30: 481⁃490. …
histone acetylation change on the … renal fibrosis in diabetes. Am J Nephrol, 2009, 30: 481⁃490. …
[PDF][PDF] DNA 甲基化和组蛋白乙酰化修饰调控腹膜纤维化的研究进展
徐柳青, 马姝琛, 施映枫, 庄守纲, 刘娜 - 中华肾脏病杂志, 2016 - cjn.org.cn
… Defective histone acetylation is responsible for the … I histone deacetylase ameliorates renal
fibrosis and inhibits … The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, …
fibrosis and inhibits … The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, …
[PDF][PDF] 表观遗传学与糖尿病肾脏病
林乔轩, 马屹茕, 丁国华 - 中华肾脏病杂志, 2020 - cjn.org.cn
… Histone acetylation and its modifiers in the pathogenesis of … Involvement of p300/CBP and
epigenetic histone acetylation … induced fibrosis and renal damage by the inhibition of histone …
epigenetic histone acetylation … induced fibrosis and renal damage by the inhibition of histone …
[PDF][PDF] 组蛋白乙酰化修饰调控腹膜纤维化的研究进展
金德伟, 陶敏, 施映枫, 马晓燕, 刘娜 - 中华肾脏病杂志 - cjn.org.cn
… 发生 翻译后修饰(post⁃translational modification).但由于组蛋 … Histone acetyltransferase
inhibitor C646 reverses epithelial … induced fibrosis and renal damage by the inhibition of histone …
inhibitor C646 reverses epithelial … induced fibrosis and renal damage by the inhibition of histone …