表观遗传干预大脑年轻化: 锚定年龄相关的转座子

A Sfera, L Fayard, C Osorio, A Price - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… of epigenetic cancer drugs, brought neurodegeneration … may lower the specific
neurodegenerative disorders triggers. … Top: The youthful DNA methylation pattern: promoter …

天然膳食化合物作为抗阿尔茨海默病药物的遗传和表观遗传靶标

WO Castillo-Ordoñez, N Cajas-Salazar… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… as epigenetic regulators to treat neurodegenerative diseases … cells DNA methylation pattern
is an example of an epigenetic … This mechanism is essential to preserve the DNA methylome

表观基因组可成为帕金森病的治疗标靶?

SV Hegarty, AM Sullivan, GW O'Keeffe - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
patterns have the potential to be employed as epigenetic biomarkers … and DNA methylation
are the most common epigenetic … This highlights the importance of the DNA methylome in PD-…

揭示阿尔茨海默病中的DNA 甲基化: 基于阵列的人脑研究综述

VC Alves, E Carro, J Figueiro-Silva - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… of epigenetic mechanisms, particularly DNA methylation. This … its association with altered
methylation patterns. Despite the … ’s disease (AD) is an insidious neurodegenerative disorder

DNA 甲基转移酶1 调节神经元的存活

J Symmank, G Zimmer - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… of longevity, age-associated diseases as well as during the … networks epigenetic mechanisms
like DNA methylation and … disease, an age-related neurodegenerative disorder, 5-methyl…

非CpG 甲基化降低是脊髓损伤后重要的表观遗传靶点

Z Wu, C Li, R Zhu, Y Cao, TC Chen… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
pattern of DNA methylation in the spinal cord following injury and identified reduced nonCpG
methylation as an epigenetic … in neurodegenerative and neurotraumatic diseases by high-…

GBA, SNCA 和VPS35 3 种基因突变与中国汉族人群阿尔茨海默病无关: 病例-对照研究

YF Wen, XW Xiao, L Zhou, YL Jiang, Y Zhu… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… , being the two most common neurodegenerative disorders, they have shared mechanisms
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

控制神经发生和直接神经元重编程的转录后机制

E Papadimitriou, D Thomaidou - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… due to sophisticated mechanisms of epigenetic, transcriptional, and … models of
neurodegenerative diseases and CNS trauma. … Genome-wide mapping studies have shown that …

小鼠Müller 神经胶质细胞重编程的研究: 十年回顾和未来展望

Z Yin, J Kang, X Cheng, H Gao, S Huo… - 中国神经再生研究(英文版), 2025 - sjzsyj.com.cn
… the defining features of neurodegenerative diseases (Cheng et … Thus, we speculate that
epigenetic remodeling is essential … by restoring young DNA methylation patterns. The beneficial …

RNA 修饰诱导剂Salsolinol 通过YAP1 和自噬介导多巴胺能神经元死亡

J Wang, Y Ran, Z Li, T Zhao, F Zhang… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
… Research has shown that YAP1 regulates the level of autophagy, and the … diseases, such
as neurodegenerative disease, pancreatic cancer, endometriosis, and diabetic kidney disease (…