… We are utilizing a metabolically competent human liver cell line as the parental line for … or
clarify specific drug-transporter interactions by comparison of drug transport between the wild-…

… and application of organoids and OOC, and analyse the policies, research, development
and industrial … A novel human colon signetring cell carcinoma organoid line: establishment, …

… brain organoids are of immense interest as more precise human neural … drug screening,
chemical toxicity assessment and personalized therapies. A key advantage in drug development …

… Human organoids for predictive toxicology research and drug development[J / OL]. Front …
CONCLUSION This study has constructed a human kidney organoid model and verified the …

… to in vitro models using human resource cells or cellular components. … drug-induced toxicity
and the drug-induced toxicity remains a major problem in developing new drugs, a predictive …

… human embryos in vitro. In addition, technology breakthroughs of iPSC-based organoid
construction make it possible to study … -derived neural constructs for predicting neural toxicity [J].…

… in organoid model concerning the physiological features, … Comparing predictive drug
nephrotoxicity biomarkers in … dimensional testicular organoid: A novel tool for the study of human …

… which are predictive of human clinical results. Co-culture of … be used for predicting therapeutic
efficacy, toxicity, and interactions … Recently, organoids, self-organized 3D tissue constructs …

… models for predicting human responses to various drugs and … such as life science, drug
discovery, personalized medicine, food… research, drug testing, personalized medicine, toxicity …

… prospect the future development of organoid products in the … system using primary human
gut organoids to capture multiple … FDA’s predictive toxicology roadmap. 2017-12-30 [2023-07-…