反向分子对接应用于黄曲霉素B1 毒性机制及药物Oltipraz 靶点的探究

张裕, 郭丽梅 - 中国药学(英文版), 2014 - jcps.bjmu.edu.cn
… server TarFishDock with the intention of improving the use of this … As mentioned above, the
rationality of the method is confirmed … of Oltipraz, like chk1 and androgen receptor. Altogether, …

抗雄激素药物治疗去势抵抗型前列腺癌的机制研究进展

王前奔, 吴大勇 - 中国肿瘤临床, 2015 - cjco.cn
… , anti-androgen therapy remains an important treatment option because androgen receptor
… : structure, role in prostate cancer and drug discovery[J]. Acta Pharmacol Sin, 2015, 36(1):3-…

Erxian Tang (二仙汤)—Introduction of a Chinese herbal formula, clinical practice, and experimental studies

J Li, JT Li, J Fu - Chinese Journal of Integrative Medicine, 2007 - Springer
… principle of creation and rationality in drug choice, with the … not hot, and enjoying the
therapeutic merits of warming Shen-… and 72 h in vitro survival rate significantly increased (P<0.01)…

晚期非小细胞肺癌免疫治疗的研究进展

程颖 - 肿瘤防治研究, 2021 - zlfzyj.com
… More patients treated with immunotherapy have achieved long-term survival. At present,
immunotherapy is still a hot research hotspot. In order to better understand the development

[PDF][PDF] 三阴性乳腺癌精准诊疗的挑战与展望

蒙玉华, 周仁钰, 陈炫兆, 陆元志 - 生命科学, 2021 - lifescience.sinh.ac.cn
… 雄激素受体(androgen receptor, AR) 阳性的TNBC 是一个独特的乳腺癌亚型,约占总体TNBC
的… after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov, …

[HTML][HTML] 靶向同源重组修复的抗肿瘤研究进展

钟振兴, 彭鑫, 孔德新 - 药学学报, 2020 - html.rhhz.net
… Figure 4 Schematic diagram of regulatory pathways of HR and potential therapeutic targets.
ATR: Ataxia telangiectasia and Rad3 related gene; CHK1: Checkpoint kinase 1; CDK1/2: …

绝经后妇女血清激素受体共激活因子3 与骨密度, 骨转换水平的相关性

展磊, 魏秋实 - 中国组织工程研究, 2017 - cjter.com
… SRC-3 silencing can inhibit cell proliferation and survival stimulated by estrogen in ERα-…
[7] showed that osteoblast-targeted overexpression of ERα increased the BMD in mice. In …

[PDF][PDF] 上合组织国家的科学研究: 协同和一体化

ML Yulevna, RE Aleksandrovna - … OF THE SCO COUNTRIES: SYNERGY AND … - naukarus.ru
development of technology and the rapidly changing labor market, characteristic of modern
times, inevitably lead to the need for continuous improvement … on the post-rational logic of the …

[PDF][PDF] 肝X 受体激动剂GW3965 对人结肠癌细胞奥沙利铂耐药的逆转作用及机制

谭湘洲, 王然, 文俏程, 莫砚群, 吴瑞平, 陈志康 - 中国普通外科杂志, 2017 - zpwz.net
… of 5-fluorouracil: a rational approach to improving therapeutic outcomes[J]. Journal of the …
Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces …

[PDF][PDF] microRNA-378 与肿瘤血管生成的研究进展

肖洒, 胡金芳, 陈思羽, 吴科锋… - Progress in Modern …, 2019 - biomed.cnjournals.com
Androgens enhance ischaemia-mediated neovascularisation by stimulation of HIF-1琢and …
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and …