… both the lipophilic and hydrophilic segments, the drug loading … Furthermore, the in vitro and
in vivo cytotoxic activity of TPGS … solubilized some poorly watersoluble drugs is the polyvinyl …

… Water soluble free drug … Second, they typically have lipophilicity with oils and other lipids.
Phytosomes can improve the lipophilicity of active constituents significantly, which could be …

… On the other hand, they are relatively more lipophilic in comparison to … correlated well with
their respective dopaminergic toxicities. In agreement with this proposal, the water soluble anti-…

… poor solubility leads to unavailability of the drugs for absorption. Resveratrol was a lipophilic
… Apart from water soluble OSCs, the bioavailability and metabolism of oil-soluble OSCs were …

… Both the in vivo and in vitro studies have demonstrated that artemisinin B might play its
anti-… In a mouse model of experimental cerebral ischemia/reperfusion injury, a water-soluble …

… Abstract: The technology of lipid-drug conjugates is developed on the basis … drugs via
increasing the lipophilicity of hydrophilic or poorly soluble drugs to promote the absorption of drugs …

… The ability of curcumin to bind amyloid is thought to be due to its structural similarity to the
water-soluble dye Congo red, which is able to stain amyloid plaques. In addition, curcumin …

… amphiphilic, and lipophilic character. Several nitroxides, such as TEMPO, are water soluble
and, being of low molecular weight, can readily enter intact cells and cellular compartments." …

… can increase the solubility of lipophilic drugs in the form of mixed micelles, assisting polar …
of poorly watersoluble drugs and peptide/protein-based therapeutics or vaccines [J].Drug Deliv…

… Abstract: BCS Ⅱ drugs are characterized by low solubility and high permeability. Improving
… Recent strategies to increase the solubility of poorly-soluble drugs may unexpectedly result …