… , cardiac muscle, smooth muscle and brain[6]. … Restoration of human dystrophin following
transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice. Cell …

… dystrophy (DMD) is an X-linked, recessive and lethal genetic … gene mutation and molecular
mechanism study of the disease, which requires reliable disease models such as mdx mouse …

… with dystrophic muscle cells and restored dystrophin expression in duchenne muscular …
different in vivo potential to differentiate into muscle cells when injected in dystrophic mice. …

… genome editing partially restores dystrophin expression in a mouse model of muscular
dystrophy… /idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved …

… gene editing technology to construct Dmd gene mutant mice … myocardial (Heart) muscles
of 9-month old DmdMu/Y mice … knockin mouse model of Duchenne muscular dystrophy and …

… genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy
… In vivo genome editing restores haemostasis in a mouse model of haemophilia. Nature. …

… ameliorate the dystrophic phenotype in a DMD mouse model. … Preservation of the cardiac
function in infarcted rat hearts by … Stem cells for cardiac repair in acute myocardial infarction. …

… gene editing tool for a broad spectrum of applications. In this review, we discuss the recent
development and applications of gene editing … In vivo gene editing in dystrophic mouse …

… This gene editing technique,compared with zinc finger nuclease(ZFN)and transcription
activator-like effector nuclease (TALEN),is cheaper and more efficient. Therefore,since its first …

… ) is the most frequent form of adult muscular dystrophy, transmitted with autosomal dominant
… Supporting our findings, a recent study conducted on DM1 transgenic mice has shown that …