Background: Inadequate dietary protein intake causes adverse changes in the morphology
and function of skeletal muscle. These changes may be reflected in early alterations in
muscle messenger RNA levels. Objective: This study assessed whether inadequate protein
intake differentially affects skeletal muscle transcript concentrations and expression profiles
in older adults. Design: Twenty-one older men and women (aged 55–80 y) consumed
controlled diets that provided 1.2 g protein· kg− 1· d− 1 (adequate protein) for 1 wk and then …