过氧化氢介导促炎细胞-细胞信号传导: 炎症的新治疗靶点?

D Gunawardena, R Raju, G Münch - 中国神经再生研究(英文版), 2019 - sjzsyj.com.cn
… that hydrogen peroxide can act as an extracellular signaling … increase of intracellular catalase
activity and therefore this mechanism is not the major cause for the downregulation of TNF-…

共济失调-毛细血管扩张突变在小脑完整性和功能中起重要作用

Y Mitiagin, A Barzilai - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… deficiency specifically increases the levels of cerebellar hydrogen peroxide. High levels of
… In the nucleus, NRF1 upregulates nuclear-encoded mitochondrial genes thereby increasing

PGC-1α 在CH1 细胞中通过ATP 和ROS 调控细胞周期

X Fu, K Yao, X Du, Y Li, X Yang, M Yu, M Li… - Journal of Zhejiang …, 2016 - Springer
… were accompanied by up-regulation of the … cellular hydrogen peroxide content was high
but cell death was not induced. Effects of the treatment on protein expression and cell growth

线粒体功能障碍与质量控制: 蛛网膜下腔出血的核心

J Zhang, Q Zhu, J Wang, Z Peng, Z Zhuang… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… Fe2+ can react with hydrogen peroxide in a Fenton reaction to … Another study found that
melatonin mediated the upregulation of … genes, including TFAM, thus increasing mitochondrial …

西红花酸对晚期糖化终产物诱导内皮细胞晚期糖基化终产物受体表达的抑制作用

向敏, 钱之玉, 周成华 - 中国临床药理学与治疗学, 2008 - manu41.magtech.com.cn
… by ROS, particularly hydrogen peroxide, yields the fluorescent … resulted in a great increase
in extracellular superoxide ion ( … inhibited the up-regulation of RAGE gene expression in BEC …

中枢神经系统的神经炎症和神经胶质激活: 代谢观点

A Virtuoso, C De Luca, SA Korai, M Papa… - 中国神经再生研究(英文 …, 2023 - sjzsyj.com.cn
… radicals (Sod1 and Sod3), hydrogen peroxide (Cat), fatty acids … ], reactive astrocytes show
increased oxidation of fatty acids as … /LXR that upregulates ABCA1 and ABCG1 genes. ABCA1/…

铁死亡: 脑卒中的潜在治疗靶点

C Liu, G Wang, W Han, Q Tian, M Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… When intracellular Fe2+ increases, hydroxyl free radicals can be generated … nuclear
translocation, activated YAP can upregulate multiple ferroptosisrelated transcriptional target genes, …

Reappraisal of metallothionein: Clinical implications for patients with diabetes mellitus: 重新评价金属硫蛋白: 对糖尿病患者的临床意义

Y Park, J Zhang, L Cai - Journal of Diabetes, 2018 - Wiley Online Library
… ]) and non-radical derivatives of O 2 such as hydrogen peroxide (H 2 O 2 ).10 Mitochondria
are … Genes upstream or downstream of the UPR are often found to be upregulated in several …

神经可塑性和脑退化机制: 衰老过程中的保护策略

M Toricelli, AAR Pereira, GS Abrao… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
… Additionally, increasing cellular senescence and the release … the expression of mitochondrial
genes encoded by the nucleus… Hydrogen peroxide (H2O2) is one example of a stressor that …

大脑中的端粒酶和mTOR: 线粒体连接

S Miwa, G Saretzki - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… For example, it can localize to mitochondria under increased stress and protect cells in vitro
… These data are in line with previous findings from our group about increased mitochondrial …