… Therefore, damage to the brain caused by oxidative stress … iron is the most likely route by
which it may induce oxidative … tau polymerization, protein oxidation, and subsequent alterations …

… , constitute the designated reactive species of oxygen (ROS). … of oxidative stress are
the increase in the formation of oxidized … Common catalase is a tetramer with four ironcontaining …

… , is able to bind free iron and, thus, to block both oxidative transformation of DA into its toxic
… the oxidative stress and consecutive accumulation of neurotoxic derivates of the DA oxidation …

… are defined by inflammation and the damage neurons undergo due to oxidative stress. A
primary … oxidation and memory deficits in a mouse model of Alzheimer disease. J Biol Chem …

… chemistry, that triggers oxidation of polyunsaturated fatty acids … , IRP1 is a bifunctional
iron/reactive oxygen species (ROS) … to attenuate iron accumulation, oxidative stress, and neuronal …

… tion, and oxidative stress as well as Parkinson's disease. He is … PD and Alzheimer's disease
share many potentially common … of iron mentioned are as follows: chelated iron is bound to …

… from oxidation, intracellular H2O2 and OH• indirect oxidative … brain iron, and iron-induced
oxidative damage has been … Parkinson's disease and lessons learned from Alzheimer's disease…

… oxidative damage triggered by reactive oxygen species and … in the generation of oxidative
stress in PD and identified … , DA oxidation may occur spontaneously in the presence of iron …

… Aβ accumulation and oxidative stress strongly suggests a … one Aβ molecule binds the heme
iron via H13 while a second … sequence among the tested species with only few mutations (…

… oxygen species (ROS) in cells and tissues. ROS causes cell damage due to oxidation of …
The brain is vulnerable to oxidative stress because of its high iron content, which results in …