… There is hope that protein kinase inhibitors would provide new directions for the treatment
of hypopharyngeal cancer. Key words: Hypopharyngeal carcinomaꎻ Tumorꎻ Protein kinaseꎻ …

… Here,we briefly review the progress of pharmacological strategies targeting KRAS
mutated cancers. [Key words] KRAS gene; gene mutation; direct inhibition; targeting …

… Abstract: With the continuous progress of tumor treatment methods in recent years, more
and more emerging antitumor drugs have been approved to market and put into clinical use. In …

… In this review, FAK protein, the signaling pathway, and small molecule inhibitors are
briefly described, and the latest research progress in targeting the degradation of FAK using …

… In this review, we review the role of miRNAs in the formation of drug resistance and discuss
the existing problems and future directions. Key Words: Gastric cancer; Drug resistance; …

… Recently, a variety of tyrosine kinases be used as drug targets on targeted therapy and the
EGF receptor (EGFR) is the first receptor to be proposed for cancer therapy. EGFR inhibitors …

… Abstract: Drug transporters mediate different types of drugs with diverse structures across
cell membranes, affecting concentration of drugs in various tissues and organs and the …

: 真核翻译起始因子4B (eukaryotic translation initiation factor 4B, eIF4B) 在mRNA 翻译起始,
细胞存活和增殖过程中发挥着关键作用, 然而其在生物体内的生物学功能仍存在许多疑问. 本研究…