一种新兴的1 型糖尿病治疗策略: 靶向胰腺β 细胞中的PI3K/Akt 信号通路以增强其存活和功能

I Camaya, S Donnelly, B O'Brien - Journal of Diabetes, 2022 - search.proquest.com
… The tight regulation of PI3K activities enables the optimal … and increased metabolic activity,
specifically the anabolic pro… to modulate host immune responses is the primary mechanism …

间歇性张应力对小鼠破骨细胞TRPV5 基因表达的影响

彭斐, 宋玲, 戚向敏, 李亚芹, 刁艳菲… - 山东大学学报 …, 2017 - yxbwk.njournal.sdu.edu.cn
… Research advance in pathways and signal factors during the process of osteoclast
differentiation[… Relationship between novel Ca2+ channels TRPV5, TRPV6 and signal

脂肪干细胞衰老及其对神经再生的意义

C Mantovani, G Terenghi, V Magnaghi - 中国神经再生研究(英文版), 2014 - sjzsyj.com.cn
anabolic/ catabolic roles, mitochondria appear to regulate a … We can speculate that the
degree of mitochondrial activity in … intracellular signalling pathways that challenge and regulate

中枢神经系统神经变性致烟酸缺乏症的生化途径

L Fu, V Doreswamy, R Prakash - 中国神经再生研究(英文版), 2014 - sjzsyj.com.cn
… Although describing the details of all the molecular mech… -tryptophan is a highly regulated
physiological process leading … the liver which is modulated by tryptophan and glucocorticoids. …

自噬对创伤性脊髓损伤神经保护和功能恢复的调节

SK Ray - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… A mechanical or an accidental injury to the spinal cord is called the primary … on activity of
the transcription factor EB (TFEB), and both class III PI3K and TFEB are negatively regulated by …

视网膜神经血管单元自噬: 糖尿病视网膜病变的新视角

X Yang, Z Huang, M Xu, Y Chen, M Cao… - Journal of …, 2023 - search.proquest.com
anabolism and catabolism.The autophagy process is strictly … Autophagy protects cells by
regulating metabolic activity. With … Autophagy activation is the primary mechanism by which ECs …

缺血性脑卒中后肌肉病理生理学变化: 脑卒中损伤的次要后果

H Qi, D Tian, F Luan, R Yang, N Zeng - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… In muscle fiber tissue, mitochondria are important in regulating metabolism, and also a
potential signal source for regulating partial muscle protein decomposition, providing a basis for …

中枢神经系统损伤中的自噬, 焦亡, 铁死亡和程序性坏死间的相互作用

L Zhang, Z Hu, Z Li, Y Lin - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… is a regulated mechanism of action that is mediated by signal … the imbalance of anabolism
and catabolism in chondrocytes. … , downregulation of SIRT3 modulated myocardial injury by …

骨关节炎治疗的分子靶点研究进展

丁道芳, 杜国庆, 李玲慧, 宋奕, 徐勤光, 曹月龙… - 分子影像学杂志, 2015 - j-fzyx.com
… Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signaling molecule
Smad-2P in spontaneous and instability-induced osteoarthritis:role in cartilage degradation…

生长分化因子-5 (GDF-5) 促进人退行性变髓核细胞外基质表达情况的研究

X Luo, K Liu, Z Chen, M Zhao, X Han, Y Bai… - Journal of Zhejiang …, 2016 - Springer
… The IVD maintains the mechanical stability and … up-regulation catabolism of ECM, which
causes the decrease of collagen II and aggrecan via dependent complex molecular signaling