通过DNA 甲基化定量分析和前瞻性队列研究可以最佳地表现结肠直肠癌CpG 岛甲基化表型的特征

周智勇 - 世界核心医学期刊文摘: 胃肠病学分册, 2006 - cqvip.com
… a distinct genetic profile of CIMP colorectal cancer using … bimodal distribution of 80
microsatellite instability-high (MSI-H) … much higher frequencies of BRAF mutations (63%and 54%) …

微卫星稳定型结直肠癌免疫检查点抑制剂疗效预测标志物研究进展

王志强, 东帅, 李梦龙, 梁锐 - 肿瘤防治研究, 2023 - zlfzyj.com
mutational burden (TMB), POLE/POLD1 mutation, … microsatellite stability colorectal cancer,
provide a reference for the best treatment strategy for microsatellite stability colorectal cancer. …

[HTML][HTML] HES1, JAG1, MT2A 和MAFA 介导茶多酚抑制微卫星不稳定结直肠癌

许妍妍, 金黑鹰, 谈瑄忠, 刘秀芳… - Journal of Integrative …, 2010 - jcimjournal.com
… Tea polyphenol inhibits colorectal cancer with microsatellite instability by regulating the
expressions of HES1, JAG1, MT2A and MAFA. Journal of Chinese Integrative Medicine, 2010, 8(…

结直肠癌免疫治疗生物标志物研究进展

张琪, 李健 - 肿瘤综合治疗电子杂志, 2020 - jmcm2018.com
colorectal cancer (CRC), however, the clear benefit population is limited to patients with
microsatellite instability-… High tumor mutation burden and POLE/POLD1 mutation are the most …

[HTML][HTML] 最新产品价格查看产品价格

J Villanueva - promega.com.cn
… of Heterozygosity (LOH) in colorectal tumors, they found size … to have a KRAS or p53 mutation,
and show a better prognosis … and applications of the Microsatellite Instability Analysis Kit. …

[HTML][HTML] NOTCH3 基因突变与结直肠癌免疫检查点抑制剂治疗疗效的关联性

李晶, 朱静娟, 李田军, 周娜, 张晓春… - Advances in Clinical …, 2022 - hanspub.org
… NOTCH3 mutation with the prognosis of colorectal cancer (… assess the association of NOTCH3
mutation with the status of … 一线治疗高度微卫星不稳定(microsatellite instability-high, MSI-H)…

[HTML][HTML] 子宫内膜癌微卫星不稳定性分析: 微小微卫星变换的意义

梁丽, 李鑫, 农琳, 董颖, 张继新, 李东… - Journal of Peking …, 2023 - ncbi.nlm.nih.gov
… 这种分子表型称为微卫星不稳定性(microsatellite instability,MSI)。MSI肿瘤其基因组不稳定性
增加并… 本研究通过将EMC与结直肠癌(colorectal cancer,CRC)相比较,探讨分析IHC和PCR检测…

结直肠癌原发与配对转移肿瘤遗传异质性研究进展

鲁有望, 王昆华 - 遗传, 2017 - chinagene.cn
… 不稳定性(chromosomal instability, CIN) 和微卫星不稳定性(microsatellite instability, MSI)两种
类型.… KRAS mutations in primary colorectal cancer tumors and related metastases: a potential …

下一代测序技术在结直肠癌诊疗中的应用.

陈如萍, 刘蕊 - Tianjin Medical Journal, 2020 - search.ebscohost.com
… Distinct mutations of MMR gene in colorectal cancer by targeted enrichment and higt-throughput …
Consensus on the detection of microsatellite instability in colorectal cancer and other …

[PDF][PDF] 错配修复基因和结肠癌的关系

马俊丽, 曾珊 - 中南大学学报: 医学版, 2014 - researchgate.net
… , reducing gene mutations and keeping genome stability. … ,称为 微卫星不稳定性(microsatellite
instability,MSI). MSI分为高度… 直肠癌(hereditary nonpolyposis colorectal cancer,HNPCC),即…