[HTML][HTML] ASH1L 甲基转移酶在牛卵丘细胞中的表达与功能研究

崔立欣, 田雅晴, 郝海生, 邹惠影, 赵善江, 庞云渭… - 畜牧兽医学报, 2020 - xml-data.org
… (polycomb repressive complex 2,PRC2)组成基因的表达水平的影响.结果显示,ASH1L 甲基
转移酶位于牛卵丘细胞的细胞核中,呈点状分布.成功筛选到能有效干扰牛Ash1L 基因的siRNA-2 ,其…

组蛋白甲基转移酶G9a 抑制剂的研究进展

王楚慧, 赵铜鑫, 陈维琳, 湛云鹏, 张涵煦, 尤启冬… - 药学进展, 2018 - pps.cpu.edu.cn
… 抑制会导致人类造血干祖细胞(hematopoietic stem and progenitor cells,HSPCs)分化停滞[30].…
),EZH2(enhancer of zeste 2 polycomb repressive complex 2 subunit,也称KMT6A) DNA 甲基…

表观调控与神经干细胞分化

HL Tang, JH Zhu - Neuroscience Bulletin, 2007 - Springer
… Researchers have shown that the process of cortical progenitor cells differentiating into …
developY mental stage of stem cells[64]. The concept of epigenetics is opposite to genetics. …

ZEB1-AS1 洞察: 从癌症到神经退行性变的新作用

S Carelli, F Rey, E Maghraby, C Cereda - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… This leads to the upregulation of BMI1, an oncogene member of the polycomb repressive
complex 1 family, and a transcriptional repressor (Li et al., 2018). Overexpression of BMI1 has …

[PDF][PDF] EZH2 作为抗肿瘤免疫治疗靶点研究进展

李倩, 王艳林 - 生物技术通报, 2015 - biotech.aiijournal.com
… 2(Polycomb repressive complex 2,PRC2)和多梳蛋白抑制性复合 体1(Polycomb repressive
complex 1… the killing activity of immune cells against the tumor cells with over-expressed EZH2 …

转录因子BACH1 的研究进展

何韫荃, 郭阶雨, 魏香香, 孟丹 - 自然杂志, 2022 - nature.shu.edu.cn
… BACH1通过招募多梳蛋 白抑制性复合体2(poly-comb repressive complex 2, PRC2),与它的亚
… profile of hematopoietic stem cells reflects their location in a hypoxic niche [J]. Cell Stem Cell, …

解码表观遗传密码: 探索脊髓损伤恢复的新领域

BY Zhang, PY Chang, QS Zhu, YH Zhu - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… (2) H3K27me3 and H3K4me3 play domain repressive and permissive roles in gene
regulation, respectively. In this case, certain inhibitory genes against OL differentiation might be …

从昼夜节律调控角度看创面愈合

王达利, 祁放 - 中华烧伤与创面修复杂志, 2024 - zhsszz.xml-journal.net
… and cellular functions play crucial roles in the circadian rhythm regulation of wound healing.
A deeper understanding of these mechanisms is important not only to uncover the basic …

[HTML][HTML] 干扰EZH2的表达对奶山羊精原干细胞抗氧化能力的影响

蔡玉, 邓明田, 刘孜斐, 张国敏, 马键宇, 安世钰… - 南京农业大学 …, 2021 - html.rhhz.net
… 果蝇zeste基因增强子人类同源物2(enhancer of zeste homolog 2, EZH2)是polycomb抑制复合
物2(polycomb repressive complex 2, PRC2)中的成员, 具有组蛋白H3K27甲基转移酶活性, 能够…

Trolox 对猪肌肉干细胞增殖及分化的影响

胡荣蓉, 丁世杰, 郭赟, 朱浩哲, 陈益春, 刘政… - 中国农业 …, 2021 - chinaagrisci.com
… to pig muscle stem cells during their proliferation culture for 3 d, respectively. The blood
cell counter and CCK8 technology were both used to detect the influence of Trolox on the cell