… therapy (ADT) has been the mainstay of treatment in recent decades to temporarily control
the disease. With the advent of new endocrine therapy … mechanism of action and side effects. …

… , it is very important to overcome endocrine therapy drug resistance to … mechanisms and
the latest research progress of drug resistance in HR-positive breast cancer after prior AI therapy …

… To overcome previous limitations, a new generation AMS, DREAMS (drug-eluting … be
inherent defense mechanisms, may be produced by the body’s neuro-endocrine system. …

… is a mechanism of acquired resistance to endocrine therapy in … breast cancer and contribute
to endocrine therapy resistance[J]. … overcome endocrine-resistance, we have established a …

… number of approaches such as hormone therapy, nutrient supply, … : (1) Identifying the
mechanism underlying the action of RhoA … may enable neurons to overcome multiple axon growth …

… the hypothesis that resistance of hormone-receptor positive … , several stumbling blocks had
to be overcome. The first one was … Based on our model, one would predict that treatments that …

… of STAT3 in acquired drug resistance of NSCLC, … a new target to reverse drug resistance,
and provide basic theories for the new clinical treatment strategy of acquired drug resistance in …

… focused on elucidating molecular mechanisms leading to the … , treatments that modulate
neurotrophin levels have acquired … lack of a specific neurotrophic hormone. The two candidates …

… diseases and its mechanism as a target for treatment. … and a neurohormone through autocrine
or paracrine mechanisms. AM … ing the mechanism and overcoming the clinical problem of …

… Twenty-three of the patients had previously received and were refractory to at least one
endocrine therapy, and all had received at least one previous combination-chemotherapy …