小胶质细胞: 脊髓损伤的一个有前景的治疗靶点

X Zha, G Zheng, T Skutella, K Kiening… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
… factor (TNF) after SCI, which trigger inflammatory responses from … Reactive oxygen species
generated by activated microglia … with extracellular iron by secreting ferritin. By inhibiting the …

[PDF][PDF] NLRP3 炎性体在心肌梗死后心室重塑中的作用

郭雨桐, 刘文秀, 尹新华 - 心脏杂志, 2020 - heartj.cn
… role of NLRP3 inflammasome in cardiac remodeling after MI. … 外流[6],线粒体活性氧( reactive
oxygen species,ROS)的产生[7]… 活性氧 (mitochondrial reactive oxygen species,mROS)形成 (…

中枢神经系统损伤中的自噬, 焦亡, 铁死亡和程序性坏死间的相互作用

L Zhang, Z Hu, Z Li, Y Lin - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… These events lead to mitochondrial damage and activate … potential or stimulation by reactive
oxygen species (ROS), and … 5 improves microglial inflammasome activation after traumatic …

NLRP3/1 介导细胞焦亡: 阿尔茨海默病治疗策略中更有益的线索

B Hu, J Zhang, J Huang, B Luo, X Zeng… - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… by microbe or cytokines activateinflammasome activation is also induced by other factors
such as Na+ influx, an increase in intracellular Ca2+, K+ efflux, an increase in reactive oxygen

脂肪组织, 系统性炎症和神经退行性疾病

APA Boleti, PHO Cardoso, BEF Frihling… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… molecules interfere with intracellular insulin signaling, which can … Mice fed HFD show higher
levels of reactive oxygen species, … IL-1β, triggered by the inflammasome and that are unduly …

间充质干细胞源性细胞外囊泡在改善青春期酒精暴露诱发的海马NLRP3 炎症中的新作用

S Mellado, MJ Morillo-Bargues… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
… -derived extracellular vesicles ameliorated the activation of the … associated with NLRP3
inflammasome activation induced by binge … The activation of these receptors triggers an immune …

神经炎症作为将高血压与阿尔茨海默病风险增加联系起来的机制

E Bajwa, A Klegeris - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… patterns into the extracellular space. This leads to persistent … increase in active IL-1β, reactive
oxygen species, … triggers a neuropathological cycle of microglial activation, production of …

纳米载体应用在创伤性脑损伤基础研究中的优势

宋兴爽 - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… as magnetic nanoparticles and extracellular vesicles, have … Free irons play a key role in
reactive oxygen species (ROS) … damages neurons, activates astrocytes and microglia, trigger an …

易位蛋白配体对年龄相关性黄斑变性的治疗潜力

X Li, Z He, X Shu - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… is the abnormal accumulation of extracellular deposits (called … , resulting in initial dysfunction
and later death of the RPE cells … of reactive oxygen species (ROS) and activated the NRF2 …

钙离子信号介导Nod 样受体蛋白炎性小体激活的研究进展

陈雨, 徐志猛, 李萍 - 中国药科大学学报, 2021 - jcpu.cpu.edu.cn
… NLRP3 inflammasome activation induced by various NLRP3 … 包括活性氧(reactive oxygen
species,ROS)上升,钾 离子(K+)外… 细胞外信号调节激酶5 (extracellular signal-regulated kinase 5,…