Regulatory roles of the bacterial nitrogen-related phosphotransferase system
K Pflüger-Grau, B Görke - Trends in microbiology, 2010 - cell.com
K Pflüger-Grau, B Görke
Trends in microbiology, 2010•cell.comIn addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate
uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS Ntr). Although
fulfilling very different functions, both systems can communicate with each other by
phosphate exchange. PTS Ntr regulates diverse processes implicated in metabolism of
nitrogen and carbon, and is essential for virulence in some bacteria. Additionally, it plays a
role in potassium homeostasis by regulating the expression and activity of a high-and a low …
uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS Ntr). Although
fulfilling very different functions, both systems can communicate with each other by
phosphate exchange. PTS Ntr regulates diverse processes implicated in metabolism of
nitrogen and carbon, and is essential for virulence in some bacteria. Additionally, it plays a
role in potassium homeostasis by regulating the expression and activity of a high-and a low …
In addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTSNtr). Although fulfilling very different functions, both systems can communicate with each other by phosphate exchange. PTSNtr regulates diverse processes implicated in metabolism of nitrogen and carbon, and is essential for virulence in some bacteria. Additionally, it plays a role in potassium homeostasis by regulating the expression and activity of a high- and a low-affinity K+ transporter, respectively. In this article, we review recent advances in the understanding of the regulatory roles of PTSNtr in various organisms.
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