内质网应激, 自噬, 神经炎症和西格玛1 受体是抑郁症的诱因及其治疗

C Fujii, CF Zorumski, Y Izumi - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… the roles of sigma 1 receptors and pharmacological agents … function in other neurodegenerative
disease models. In the … To further test the hypothesis that prevention of LTP inhibition …

阿尔茨海默氏病的病理机制和治疗策略

Y Ju, KY Tam - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… Alzheimer’s disease is a rather complex neurodegenerative disease… Amyloid cascade
hypothesis is the most popular … Moreover, sigma-1 receptor agonists have been investigated in AD …

二甲基色胺: 神经炎症和神经保护的生化“瑞士军刀”?

A Szabo, E Frecska - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
… another receptor has been added to the greater picture: the orphan receptor sigma-1 (Sig-…
McKenna DJ (2013) A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue …

神经系统疾病中基于神经营养因子的药理学方法

M Alfonsetti, M d'Angelo, V Castelli - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… that sigma receptors, especially the sigma-1 receptor subtype … in preclinical models of
neurodegenerative diseases, such as … : towards a hypothesis of sigma-1 receptors as amplifiers of …

肌萎缩侧索硬化症中NRF2 信号级联: 弥合前景与现实之间的差距

P Tarot, C Lasbleiz, JC Liévens - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… of drugs for other neurodegenerative disorders. So far, only … protein B (VAPB) and sigma-1
receptor (S1R), regulate … disease and the “dying back” hypothesis, proposing that the …

以网络为中心的周围神经损伤药物: 治疗整个神经保护和再生的内源性机制

D Romeo-Guitart, C Casas - 中国神经再生研究(英文版), 2019 - sjzsyj.com.cn
… In support of this hypothesis, we observed that although … in different neurodegenerative
diseases such as amyotrophic … (2014) Chronic activation of sigma-1 receptor evokes nociceptive …

[PDF][PDF] 线粒体结构和功能改变对阿尔茨海默病发生的影响

安超群, 杨友涵, 魏珍, 曾燕 - 生命科学, 2021 - lifescience.sinh.ac.cn
… Abstract: Alzheimer's disease (AD) is a neurodegenerative disease characterized by …
MAM上存在大量Ca2+转运蛋白,如 Ca2+-ATPase,Sigma-1受体,兰尼碱受体(ryanodine receptors, …

Fasudil 修饰的巨噬细胞: 抗炎和调控免疫治疗实验性自身免疫性脑脊髓炎

C Liu, S Guo, R Liu, M Guo, Q Wang, Z Chai… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… and neurodegenerative diseases, including MS, Parkinson’s disease (PD), and Alzheimer’s
disease (AD… in the CNS, supporting our hypothesis that Fasudilmodified macrophages affect …

[PDF][PDF] 中国药物作用靶点研究新进展(Ⅱ)

江振洲, 范书生, 刘家岐, 俞沁玮, 张陆勇 - 药学进展, 2022 - pps.cpu.edu.cn
… (neurodegenerative disease, NDD)是症状多样化的慢性神经系统疾病,包括 阿尔茨海默病(Alzheimer's
disease,AD),帕金 森病(Parkinson's disease,… Sigma-1 受体由内质网合成并位于内质网…