sirtuin 家族与血管衰老的相关性

蒋东洋, 滕丕秀, 赵传喜, 唐勇… - 中华老年病研究电子 …, 2020 - zhlnbyjdzzz.cma-cmc.com.cn
… research progress of sirtuin family, focusing on the potential advantages of SIRT1, SIRT3 …
vascular aging, so as to provide new ideas for the study of aging related vascular diseases. …

血管内皮细胞功能紊乱与动脉粥样硬化研究进展

张稣亚, 刘红霞, 何朝勇 - 药学进展, 2021 - pps.cpu.edu.cn
… , maintaining normal endothelial function is significant to the … the factors causing endothelial
dysfunction and related clinical … SIRT1 被认为是最有前景的药物靶点,未来研究可 评估Sirtuin

有关SIRT1 改善卵巢储备功能, 调控多囊卵巢综合征的研究进展

淑芳李, 聿婷薛, 芳刘, 琛杜, 泽丽田 - 亚洲临床医学杂志, 2022 - ojs.sp.sg
1(SIRT1)参与细胞众多生理功能,如细胞凋亡,糖脂代谢,DNA修复,氧化应激,炎症反应及细胞
自噬等.另外,众多研究表明,SIRT1SIRT1对H2O2诱导的人卵巢颗粒细胞氧化应激损伤的影响[J].上海…

Naoxintong capsules (脑心通胶囊) modulates tumor necrosis factor-α-induced endothelial senescence through silent information regulator 1 signaling.

GUO Qianyun, Z Bin, Z Haitong, Z Erli… - Journal of Traditional …, 2021 - search.ebscohost.com
… promoting vascular inflammation.Silent information regulator 1 (SIRT1), an anti-ageing gene,
… Clinically, NXT improves the protection by lipoproteins and improves endothelial function in …

视网膜疾病的年龄相关驱动机制及转录因子EB 靶向治疗的神经保护作用

S Abokyi, DY Tse - 中国神经再生研究(英文版), 2025 - sjzsyj.com.cn
… in the aging retina (Luo et al., 2017). This could be due to the involvement of sirtuin 1 in …
Stimulated autophagy in ECs, enhancing microvascular dilatation and endothelial function

[PDF][PDF] 血管老化加速自发性脑出血发生的相关研究进展

司泽钰, 范小璇, 连露露, 张志刚, 封玉宁… - 国际神经病学神经外 …, 2024 - jinn.org.cn
… 沉 默信息调节因子1(Sirtuin 1,Sirt1)的N 端结构域是内源 性Sirt1 依赖性脱乙酰化的正调节因子
,通过脱… Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide …

SIRT1 激动剂白藜芦醇在眼部疾病中的研究进展

张依, 王文俊, 杨安怀 - 山东大学耳鼻喉眼学报, 2022 - ebhyxbwk.njournal.sdu.edu.cn
… stress response, mitochondrial function, and other biological processes. Sirtuin 1(SIRT1)has
been most … protection, neuroprotection, chemotherapy, and anti-aging. Oxidative stress and …

血管衰老中的表观遗传调控

丁杨楠, 吕双杰, 陈厚早, 刘德培 - 上海大学学报(自然科学版), 2019 - journal.shu.edu.cn
… : Vascular aging refers to the structural and functional changes of aorta during the aging
在老龄小鼠的血管平滑肌细胞中SIRT1 的表达量下 降, 平滑肌特异性敲除SIRT1 会促进血管紧张素…

Effect of Songlingxuemaikang (松龄血脉康) on mild essential hypertension in patients: a randomized parallel-controlled study.

ZHU Guohua, SUN Xipeng, D Cuntao… - Journal of …, 2021 - search.ebscohost.com
… might improve endothelial function through decreasing the cir… --biomarkers of endothelial
dysfunction and ageing. Mech … -induced injury by autophagy upregulation via the AMPK/SIRT1

针对神经变性的核心: FoxO, mTOR 和SIRT1

K Maiese - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
elderly population from 5% to 10% over multiple decades. Yet, the ten leading causes of
death that include cardiac … leukemia cells by activating the sirtuin 1 (SIRT1)/tuberous sclerosis …