… 提示PI3K/AKT/mTOR抑制剂联合TKI可能是转化性SCLC治疗的又一研究方向。此外研究 [21]
发现转化性SCLC细胞系中Sin3和NuRD显著上调，Sin3和NuRD是组蛋白脱乙酰化酶（histone …

… proliferation and migration of gastric cancer cells by inhibiting the STAT3/HMGB1 signaling
… apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway. …

… miR⁃1290 and its potential targets are associated with characteristics of estrogen receptor
α… PI3K/AKT/ mTOR inhibitors for advanced or recurrent endometrial cancer[J]. Cochrane …

… 此外,二甲双胍的放射增敏作用也涉及PI3K/ AKT/mTOR通路的… Molecular pathways: A
novel approach to targeting hypoxia … prostate cancer: reduced development of castration-resistant …

… Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer[J]. Biochem Pharmacol, …
-mediated growth in androgen dependent and castration resistant prostate cancer cells[J]. …

… /P300活性,在生长激素垂体腺瘤中抑 制PI3K/Akt/mTOR通路,起到抗肿瘤作用[67].Cortistatin A可
… Targeting transcription regulation in cancer with a covalent CDK7 inhibitor[J]. Nature, 2014, …

… apoptosis of human ovarian cancer cells by regulating the NF-κB signaling pathway …
sensitizes cisplatin-resistant human ovarian cancer cells through inactivation of the PI3K/AKT/mTOR …

… apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant
prostate cancer [ J… 姜黄素下调PI3K/ AKT/ mTOR通路抑制人肝癌细胞系增殖[J].基础医学与临 …

… a definite effect, so the exploration of new targeted drugs is promising for meningioma treatment.
… tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer. …

… progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist
[J… cancer growth through the suppression of PI3K/AKT/ mTOR signaling pathway [J]. Onco …