… Fujian Medical University were recruited after inquiry of disease history, general physical …
syndrome score. At the same time, it can overcome donepezil's common problems of insomnia, …

… a number of studies have been developed in mice models. A recent study using APP/PS1
transgenic mice showed that chronic sleep deprivation abnormal expression of clock genes in …

… factors contributing to Alzheimer’s disease. In Alzheimer’s disease drug development, many
… as cognitive decline, epileptiform symptoms, insomnia and agitation. As shown in Additional …

… harmful Aβ species and therefore protect from their neurotoxic effects. Sleep problems are
among the lifestyle factors that are associated with a greater risk to develop dementia. Around …

… effects adopted for sleep difficulties in Alzheimer’s disease … for factors influencing insomnia
in Alzheimer’s disease patients and … Therefore, Alzheimer’s disease patients need to develop …

… develop acupuncture research with a strong clinical basis and demonstrate the definite
curative effect, such as in diseases … of acupuncture in treating insomnia and improving sleep …

… JTP could relieve insomnia through enhancing monoamine … also relieve psychiatric disorders
(eg insomnia and depression).… investigated the treatment effects of JTP on insomnia and its …

… , 31% of primary insomnia patients suffer from moderate … insomnia and anxiety, with 54%
of primary insomnia patients having both conditions concurrently. The problems that insomnia …

… populations in developed countries, the disease is becoming … targets to develop drugs able
to slow down or arrest disease … peripheral side effects, such as tachycardia and insomnia. …

… risk of developing Alzheimer-like dementia after severe acute respiratory syndrome coronavirus
2 … , mood, and anxiety disorders; substance use disorder; and insomnia. Among 236,379 …