… healing by downregulating the NLR family pyrin domain containing 3 (NLRP3) inflammasome in diabetic rats: 硫酸乙酰肝素在糖尿病大鼠中通过下调NLRP3 炎症小体 …

T Wang, J Zhao, J Zhang, J Mei, M Shao… - Journal of …, 2018 - Wiley Online Library
… the NLRP3 inflammasome and cleaved IL- during the wound … Reducing levels of the
NLRP3 inflammasome is one of the … treatment decreased levels of NLRP3 and ASC in rats. After …

NLRP3 炎症小体在眼和大脑与年龄相关疾病发病机制中的重要作用

JJ Maran, OO Mugisho - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Activation of the NLRP3 inflammasome appears to be a common denominator in the
pathogenesis … found elevated expression of NLRP3, caspase-1, and IL- than in healthy controls, …

[HTML][HTML] … nuclear factor-kappa B signaling pathway and Nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing 3 inflammasome …

Z Zhenghua, JI Jianbin, W Hongxia… - Journal of Traditional …, 2023 - ncbi.nlm.nih.gov
… and ASC were significantly decreased in QCS treatment. … Then NLRP3 inflammasome
activation under the action of the … molecules, IL- and IL-18 cause a severe inflammatory reaction …

基于NLRP3 炎症小体探讨中医药对糖尿病动脉粥样硬化的机制及作用: 研究综述

远佳瑶, 符宇, 冯志海, 桑锋, 邵明义, 李蕾蕾 - 中国结合医学杂志(英文版) - en.cjim.cn
Activation of the NLRP3 inflammasome leads to the secretion of the proinflammatory …
the NLRP3 inflammasome in the pathogenesis and potential Chinese medicine treatment of …

Increased T cell immunoglobulin and mucin domain containing 4 (TIM‐4) is negatively correlated with serum concentrations of interleukin‐1β in type 2 diabetes: 2型糖尿病中TIM …

P Zhao, H Wang, T Li, C Lei, X Xu, W Wang… - Journal of …, 2016 - Wiley Online Library
… of the essential role of IL- in chronic inflammation in T2D … in the pathogenesis of T2D
by modulating the NLRP3 … 4 on IL- secretion and regulation of the NLRP3 inflammasome

NLRP3 炎性小体: 脑损伤的潜在治疗靶标

S Ismael, HA Ahmed, T Adris, K Parveen… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
… of the NLRP3 inflammasome in the pathophysiology of TBI, … NLRP3 inflammasome
activation is involved in many chronic … mediators IL- and IL-18. Pharmacological inhibition of …

[HTML][HTML] NLRP3 炎症小体在膝关节骨性关节炎中的研究进展

张涛, 沈万玺, 马玉林, 党修亭, 郑峰 - Advances in Clinical Medicine, 2023 - hanspub.org
role in the pathogenesis of KOA. In this article, we reviewed the mecha-nism of NLRP3
inflammasome activation … 激活pro-IL-产生IL-外,它还可促进炎症反应,并导致过量产生IL-,从而…

[HTML][HTML] NLRP3 炎症小体与儿童自身炎症性疾病研究进展

LI Yandie, LU Meiping - Journal of Zhejiang University (Medical …, 2017 - ncbi.nlm.nih.gov
NLRP3 inflammasome in the pathogenesis of autoinflammatory diseases. … IL-以及IL-1受
体基因表达上调 [ 29] 。在日本发现一例3岁JIA患儿存在NLRP3 E378K位点基因突变,且血清IL-

脂多糖联合三磷酸腺苷对肺上皮细胞来源A549 细胞IL-分泌的影响及其机制研究

W Mei-ju, W Chang-zheng… - Jie Fang Jun Yi Xue …, 2016 - search.proquest.com
… A549 cell lines increased by treatment of LPS alone compared with … activating pattern
recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3

[PDF][PDF] … 健脾汤) attenuates inflammatory re-sponses by suppressing NOD-like receptor family pyrin domain-con-taining 3 inflammasome activation in dextran sulfate …

J Zhang, X Kang, M Sun, S Zhang - J Tradit Chin Med, 2021 - researchgate.net
… In addition, we detected the mRNA expression levels of IL- … suppression of NLRP3
inflammasome activation by QRJPD. … IL- and IL-18 are central players in the pathogenesis of …