[PDF][PDF] 药物动力学和药效动力学结合在抗菌药物研发和临床治疗中的应用

J SHI - 中国临床药理学与治疗学, 2007 - manu41.magtech.com.cn
… use of Monte Carlo simulation, one can bridge the preclinical to Phase II … kinetic models A
useful approach to assess antibacterial efficacy is to use in vitro PD models based on time-kill