Cytokines as therapeutic targets in SLE
L Rönnblom, KB Elkon - Nature Reviews Rheumatology, 2010 - nature.com
… Cytokines targeted by agents in active clinical trials of SLE are indicated in red. Potential
cytokine targets for SLE therapy … In the following section, we discuss anticytokine therapies for …
cytokine targets for SLE therapy … In the following section, we discuss anticytokine therapies for …
[HTML][HTML] Many cytokines are very useful therapeutic targets in disease
M Feldmann - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
… therapeutics targeting cytokines. Why is this the case? As in RA, a large number of cytokines
are upregulated, but therapeutics … in asthma (21), nor did therapeutics blocking IL-4 (22). …
are upregulated, but therapeutics … in asthma (21), nor did therapeutics blocking IL-4 (22). …
Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases
GE Fragoulis, S Siebert, IB McInnes - Annual review of medicine, 2016 - annualreviews.org
… of therapies targeting these cytokines and their receptors. Herein, we briefly describe the
properties and interactions of IL-17 and IL-23 (forming the IL-23/-17 axis) and present the main …
properties and interactions of IL-17 and IL-23 (forming the IL-23/-17 axis) and present the main …
Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… Cytokines are therefore attractive therapeutic targets in these conditions. Anticytokine therapy
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
[HTML][HTML] Inflammatory cytokines and chemokines as therapeutic targets in heart failure
A Hanna, NG Frangogiannis - Cardiovascular Drugs and Therapy, 2020 - Springer
… Finally, we discuss the promises and challenges of cytokine and chemokine targeting in …
from targeted cytokine therapeutics [153]. Third, the need for chronic administration of cytokine …
from targeted cytokine therapeutics [153]. Third, the need for chronic administration of cytokine …
[PDF][PDF] Cytokines as therapeutic targets: advances and limitations
C Scheinecker, K Redlich, JS Smolen - Immunity, 2008 - cell.com
… Biological therapies targeting cytokines, T cells, or B cells have improved outcomes of
inflammatory diseases. However, many issues remain open: What is the best target? How …
inflammatory diseases. However, many issues remain open: What is the best target? How …
Immunopathobiology and therapeutic targets related to cytokines in liver diseases
… these cytokines in the liver are briefly summarized. Several cytokines have great therapeutic
potential, and some are currently being tested as therapeutic targets in clinical trials for the …
potential, and some are currently being tested as therapeutic targets in clinical trials for the …
[HTML][HTML] Cytokines in sepsis: potent immunoregulators and potential therapeutic targets—an updated view
W Schulte, J Bernhagen, R Bucala - Mediators of inflammation, 2013 - hindawi.com
… The actions of individual pro- and anti-inflammatory cytokines are described in more detail …
of cytokine actions in recent years, a number of therapeutic strategies targeting cytokines and …
of cytokine actions in recent years, a number of therapeutic strategies targeting cytokines and …
Cytokines in Sjögren's syndrome: potential therapeutic targets
N Roescher, PP Tak, GG Illei - Annals of the rheumatic diseases, 2010 - ard.bmj.com
… targets. The pharmaceutical industry shows little interest in developing biological therapies
primarily for SS; therefore we will focus on cytokines that could be targeted with biological …
primarily for SS; therefore we will focus on cytokines that could be targeted with biological …
[HTML][HTML] Cytokines as therapeutic targets for cardio-and cerebrovascular diseases
… Nevertheless, cytokine inhibition is … of cytokines on atherosclerosis, myocardial infarction,
and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and …
and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and …
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