转录因子HIF-1α 及其信号通路在疾病发生中的作用研究进展
杨梦思， 周娜， 王志钢， 郝慧芳 - 生物技术通报, 2016 - biotech.aiijournal.com
… We reviewed the role of transcription factors HIF-1α and its … 另一个是反式激活结构域-N(transactivation
domain-N terminal,… 因子(factorinhibiting hypoxia-inducible factor,FIH-1), 将HIF1α C …
domain-N terminal,… 因子(factorinhibiting hypoxia-inducible factor,FIH-1), 将HIF1α C …
[PDF][PDF] 缺氧诱导因子与肾细胞癌关系的研究进展
田立志， 沈阳， 项鹏程， 许涛， 王晓民… - 现代生物医学 …, 2015 - biomed.cnjournals.com
… 摘要:缺氧诱导因子(hypoxia inducible factor,HIF) 对维持肿瘤… growth factor transcription
by endothelia lPAS domain protein1 (… Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible …
by endothelia lPAS domain protein1 (… Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible …
[PDF][PDF] 缺氧诱导因子-1 (HIF-1) 及其在水生动物中的研究进展
蔡秀红， 黄贻涛， 张子平， 王艺磊 - 农业生物技术学报, 2014 - journal05.magtech.org.cn
… factor mediating this response is the hypoxia- inducible factor-… kinase inhibitor PD98059
blocks the trans- activation but not … stabilization of hypoxia-inducible factor-1α by modulating an …
blocks the trans- activation but not … stabilization of hypoxia-inducible factor-1α by modulating an …
[HTML][HTML] HIF-VEGF-Ang-2 信号转导介导的滑膜血管新生在类风湿关节炎中的作用
甘珮荣， 刘超， 吴虹， 董心同， 柯江涛， 陈芳园 - 药学学报, 2021 - html.rhhz.net
… ) 结构域,反式激活结构域(transactivation domains, N-TAD, C-TAD) … HRE of VEGF, activating
VEGF transcription. VEGF-VEGFR … in expression of hypoxia-inducible factor-1α in rheumatoid …
VEGF transcription. VEGF-VEGFR … in expression of hypoxia-inducible factor-1α in rheumatoid …
[HTML][HTML] HIF-1 在肝癌中作用的研究进展
罗东君， 吴俊华 - 世界华人消化杂志, 2014 - wjgnet.com
… 式激活区(transactivation domain, TAD)… inhibitory domain, ID), 在常氧情况下明显抑制HIF-1α的
蛋白活性. 此外, 在结构中还存在氧依赖性降解结构域(oxygen-dependent-degradation domain…
蛋白活性. 此外, 在结构中还存在氧依赖性降解结构域(oxygen-dependent-degradation domain…
[PDF][PDF] 缺氧诱导因子及其研究进展
任玥衡， 郝传明 - 中国血液净化, 2014 - cjbp.org.cn
… 激活区 域(N- terminal transactivation domain, NTAD),决定了… Regulation of the hypoxia-inducible
transcription factor 1 … asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (…
transcription factor 1 … asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (…
缺氧诱导因子和早发性脑弥漫性白质损伤: 小鼠基因研究
F Guo, S Zhang - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… Hypoxia-inducible factors (HIFs) are transcriptional … of the C-terminal transactivation domain
as present in HIF1α and … the hypothetic “paracrine” modulation of OPC differentiation by …
as present in HIF1α and … the hypothetic “paracrine” modulation of OPC differentiation by …
[HTML][HTML] 缺氧诱导因子-2 在头颈部肿瘤中的研究进展
高伟， 李钦 - Advances in Clinical Medicine, 2020 - hanspub.org
… -2 (HIF-2), as a member of the hypoxia inducible factor family, is closely related to the … -1α相应
结构域同源性为99%,91%和96%.其羧基端含有反式激活结构域-C (transactivation domain …
结构域同源性为99%,91%和96%.其羧基端含有反式激活结构域-C (transactivation domain …
[PDF][PDF] 低压低氧环境下喜马拉雅世居人群HIF 通路的改变
… -SIM ( PAS) domain -containing transcription factors,which are … degradation domain (ODD)
and two transactivation domains … hydroxylase acting on hypoxia-inducible factor[J]. Proc. Natl. …
and two transactivation domains … hydroxylase acting on hypoxia-inducible factor[J]. Proc. Natl. …
[HTML][HTML] 低氧对脂肪细胞发育及脂质代谢调控研究进展
刘媛， 李惠侠 - 生物工程学报, 2023 - cjb.ijournals.cn
… Hypoxia inducible factor (HIF) is a major transcription factor … 氨酰羟化酶(prolyl hydroxylase
domains, PHD)快速羟基化,羟基… in mice through inhibition of PKM2 transactivation. American …
domains, PHD)快速羟基化,羟基… in mice through inhibition of PKM2 transactivation. American …