[HTML][HTML] 腺鳞癌转化在肺癌耐药中的功能和机制研究

陈玥清, 陈雨婷, 童欣媛, 季红斌 - 生物医学转化, 2021 - swyxzh.ijournals.cn
squamous transition. Such transition confers lung tumors with drug resistance in mouse
models… This review will summarize current research progress of the transition from lung ADC to …

[HTML][HTML] MET 基因改变的非小细胞肺癌靶向治疗耐药机制及治疗策略

LI Shuzhan, X ZHANG - Chinese Journal of Lung Cancer, 2023 - ncbi.nlm.nih.gov
… to epithelial transition factor (MET) gene alterations involve … -small cell lung cancer with MET
alterations, and resistance to these … Off-target resistance includes activation of MET cascade …

[HTML][HTML] 驱动基因阳性肺腺癌在靶向治疗中病理类型转化的机制与治疗策略

谢同济, 李研, 邢镨元 - Chinese Journal of Lung Cancer, 2020 - ncbi.nlm.nih.gov
… The common mechanisms of drug resistance include secondary … transformation includes
the transformation from lung ADC to small cell lung cancer (SCLC), squamous cell carcinoma (…

[HTML][HTML] 合并MET 基因变异的非小细胞肺癌治疗研究进展

陈然, 江昌, 唐俊, 马丽, 张树才 - Chinese Journal of Lung Cancer, 2022 - ncbi.nlm.nih.gov
… -epithelial transition factor, MET)长期以来被认为是非小细胞肺癌(non-small cell lung cancer,
NSCLC… In addition, when MET amplification occurs after resistance to EGFR tyrosine kinase …

[HTML][HTML] 2023 年《 NCCN 肿瘤临床实践指南: 非小细胞肺癌》 更新解读

ZHU Lingling, W Ting, WU Juan… - … of Lung Cancer, 2023 - ncbi.nlm.nih.gov
cancer is the malignant tumor with the highest morbidity and mortality in China. Non-small cell
lung cancer … , which reflects the latest advances in international lung cancer research. This …

[PDF][PDF] 保罗样激酶1 保罗盒结构域: 肿瘤治疗的新靶标

付正豪, 苏美华, 刘晓平, 陈云雨 - 生物工程学报, 2020 - researchgate.net
… of these inhibitors is the serious off-target effect due to the … strongly suppress esophageal
squamous cell carcinoma (ESCC) … inhibitors via chemical modifications in lead compounds or …

[HTML][HTML] 2022 年《 NCCN 非小细胞肺癌临床实践指南》 更新解读

钱剑男, 杨邵瑜, 陈雪琴, 马胜林 - 实用肿瘤杂志, 2022 - xml-data.org
cancer centers, aiming to provide a better, more efficient and more appropriate management
model for cancer … experts and cancer patients have access to the latest cancer prevention, …

长链非编码RNA 在衰老过程中的分子标志及其对衰老相关疾病的显著影响

SAM Sherazi, A Abbasi, MU Abdullah Jamil… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… in off-target results. However, the developed catalytic oligonucleotides with base modifications
for … play a significant role in cancers such as hepatocellular carcinoma, bladder cancer, …

[HTML][HTML] 晚期肺腺癌患者获得性EGFR-TKI 耐药后治疗的研究进展

王康, 胡雪婷, 罗虎, 周向东 - Advances in Clinical Medicine, 2021 - hanspub.org
… status of acquired EGFR-TKI post-drug resistance treatment in patients with advanced lung
… cell lung cancer, SCLC)或肺鳞癌和上皮间质转化(Epithelial-mesenchymal transition, EMT).…

长链非编码RNA 在神经退行性疾病中的重要作用

W Xiong, L Lu, J Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… faces several challenges, including off-target effects, safety concerns, … of lncRNAs in chromatin
modification, transcription, and … analysis reveals the coregulation of RNA-binding proteins …