非小细胞肺癌EGFR 基因少见突变G719X 的治疗模式探索性分析

郑华, 高远, 刘赞, 钱哲, 张同梅, 李杰… - Oncology and …, 2019 - otm.tjh.com.cn
uncommon mutation of the epidermal growth factor receptor (… The objective response rate
(ORR) of first-line EGFR-TKI … It can be treated with the second- or third-generation EGFR-…

[HTML][HTML] NSCLC 非经典EGFR 突变患者临床特点及治疗预后分析

张君, 张佳梦, 毕焕焕, 王红梅 - 实用肿瘤杂志, 2021 - xml-data.org
… therapeutic efficacy of epidermal growth factor receptor-tyrosine … For those treated with TKI,
the objective response rate (ORR) was … mutations who received first-generation and second-…

EGFR非第18-21四个外显子突变晚期非小细胞肺癌对不同治疗的反应

卢红莲, 刘思阳, 周嘉莹, 揭光灵, 吴一龙 - 循证医学, 2022 - jebm.cn
… the response of epidermal growth factor receptor(EGFR)non⁃exons⁃18⁃21⁃mutated
compound mutations could also benefit from first⁃ to third⁃generation EGFR⁃TKIs. And the …

表皮生长因子受体罕见亚型敏感突变阳性肺癌的精准治疗.

李芸, 陈良安 - Chinese Journal of Oncology, 2017 - search.ebscohost.com
… with the first generation of EGFR⁃ TKIs, second generation … on “ uncommonepidermal
growth factor receptor mutations of … Good clinical response to gefitinib in a nonsmall cell lung …

[HTML][HTML] G719X/L861Q/S768I 突变非小细胞肺癌诊断及靶向治疗进展

W Yufang, J ZHENG, ZHU Yanping… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
… 发生是由于表皮生长因子受体(epidermal growth factor receptor, EGFR)发生点突变、外显…
rare mutations are mainly next-generation sequencing (NGS), digital polymerase chain reaction

第三代EGFR-TKIs 治疗晚期非小细胞肺癌的耐药机制及应对策略研究进展

何婧怡, 吴芳, 胡春宏 - 肿瘤防治研究, 2019 - zlfzyj.com
… Abstract: Targeted therapy of epidermal growth factor receptor … modality as the first-line
treatment of advanced EGFR-mutated non… of the firstand second-generation EGFR-TKIs. The third-…

[HTML][HTML] 奥希替尼在非小细胞肺癌靶向治疗中的获得性耐药机制

赵梓彤, 倪羽, 李里, 信涛 - Chinese Journal of Lung Cancer, 2020 - ncbi.nlm.nih.gov
… 激酶抑制剂(epidermal growth factor receptor-tyrosine kinase … to engender refractoriness to
first- and second-generation TKI, … EGFR C797S and other rare tertiary EGFR mutations, MET, …

[HTML][HTML] 原发T790M 突变非小细胞肺癌研究进展

王鑫, 钟殿胜 - Chinese Journal of Lung Cancer, 2019 - ncbi.nlm.nih.gov
… of the third generation of epidermal growth factor receptor (… factor and the efficacy of the first
and second generation EGFR… (droplet digital polymerase chain reaction, ddPCR)检测早期术…

[HTML][HTML] EGFR 基因少见突变型非小细胞肺癌的临床特征及应用EGFR-TKIs 治疗效果评价

史云舒, 李盼华, 李班班, 张凤鸣, 黄思远… - Chinese Journal of …, 2019 - ncbi.nlm.nih.gov
… against the epidermal growth factor receptor (EGFR) as the … complex mutations than
those with single rare mutations. … mutation system, ARMS)或二代测序技术("Next-generation" …

[HTML][HTML] 罕见CRISPLD2-NRG1 融合突变晚期混合型非小细胞肺癌1 例并文献复习

C Chunmei, YU Yang, H Meijuan - Chinese Journal of Lung …, 2024 - ncbi.nlm.nih.gov
… With the development of next-generation sequencing (NGS) detection technology, more … a
rare oncogenic driver that can lead to activation of human epidermal growth factor receptor 3 (…