Anticancer activity of bisindole alkaloids derived from natural sources and synthetic bisindole hybrids
Y Zhang, C Hu - Archiv der Pharmazie, 2020 - Wiley Online Library
… bisindole hybrids in the development of novel anticancer agents. In this review, we present a
brief account of the bisindole alkaloids … anticancer activity developed in the recent 10 years. …
brief account of the bisindole alkaloids … anticancer activity developed in the recent 10 years. …
Bisindole natural products: A vital source for the development of new anticancer drugs
M Xu, R Peng, Q Min, S Hui, X Chen, G Yang… - European Journal of …, 2022 - Elsevier
… compounds have been isolated with to the anticancer activities proved. In this paper, we
review the progress of bisindole alkaloids with the potential anticancer value extracted from …
review the progress of bisindole alkaloids with the potential anticancer value extracted from …
Indole alkaloids with potential anticancer activity
D Xu, Z Xu - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
… tinctoria L, has already been used in clinical practice for the treatment of chronic myeloid
leukemia, revealing the potential of bisindole alkaloids as putative anticancer agents [77, 78]. …
leukemia, revealing the potential of bisindole alkaloids as putative anticancer agents [77, 78]. …
Monoterpene indole alkaloids with anticancer activity from Tabernaemontana species
BMF Gonçalves, N Duarte, C Ramalhete… - Phytochemistry …, 2024 - Springer
… of new anticancer therapeutics. In this work, the anticancer activity of indole and bisindole
alkaloids … Aiming at summarizing our contribution in the study of these species, the anticancer …
alkaloids … Aiming at summarizing our contribution in the study of these species, the anticancer …
Plant anticancer agents III: Isolation of indole and bisindole alkaloids from Tabernaemontana holstii roots
DGI Kingston, BT Li, F Ionescu - Journal of Pharmaceutical Sciences, 1977 - Elsevier
… A random screening of botanical sources for anticancer activity showed that the aqueous
alcoholic extract of the roots of Tabernaemontana holstii K. Schum (family Apocynaceae) gave …
alcoholic extract of the roots of Tabernaemontana holstii K. Schum (family Apocynaceae) gave …
The current scenario of naturally occurring indole alkaloids with anticancer potential
J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
… indole alkaloids with high anticancer activity to seek for more promising preclinical/clinical
candidates; (3) modification of the lead hits to obtain novel agents with enhanced activity. …
candidates; (3) modification of the lead hits to obtain novel agents with enhanced activity. …
Monoterpenoid bisindole alkaloids
M Kitajima, H Takayama - The alkaloids: Chemistry and biology, 2016 - Elsevier
… Vinblastine (117) and vincristine, well-known antitumor bisindole alkaloids, are biogenetically
derived from the coupling of vindoline (123, Aspidosperma type) and catharanthine (124, …
derived from the coupling of vindoline (123, Aspidosperma type) and catharanthine (124, …
Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities
PF Rosales, GS Bordin, AE Gower, S Moura - Fitoterapia, 2020 - Elsevier
… to their activities as cerebral vasodilators, anticancer agents, … and biological activities of
new indoles alkaloids. Databases, … New bisindole alkaloids have also been isolated in the last …
new indoles alkaloids. Databases, … New bisindole alkaloids have also been isolated in the last …
[HTML][HTML] Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling
… bisindole alkaloids as Wnt signaling inhibitor by using a cell-based luciferase assay system,
among which, Bisleuconothine A (BLA) showed the most potent activity. … anti-tumor activity in …
among which, Bisleuconothine A (BLA) showed the most potent activity. … anti-tumor activity in …
Medicinal chemistry of bisindole alkaloids from Catharanthus
HL Pearce - The Alkaloids: Chemistry and Pharmacology, 1990 - Elsevier
… In general, aromatic substitution of the bisindole nucleus results in reduced antitumor activity.
12’, 17-Dibromovinblastine (6) shows approximately one-tenth the potency of vinblastine in …
12’, 17-Dibromovinblastine (6) shows approximately one-tenth the potency of vinblastine in …
相关搜索
- anticancer activity indole alkaloids
- bisindole alkaloids plant anticancer agents
- cytotoxic bisindole alkaloids
- synthesis of bisindole alkaloids
- bisindole alkaloid colorectal cancer cell
- bisindole alkaloids natural sources
- anticancer activity hybrids with potential
- bisindole alkaloids isolation of indole
- anticancer activity natural sources
- anticancer potential indole alkaloids