High-fat diet-induced lipidome perturbations in the cortex, hippocampus, hypothalamus, and olfactory bulb of mice

JC Lee, SM Park, IY Kim, H Sung, JK Seong… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… The effect of a high-fat (HF) diet on the lipid profiles of the cortex, hippocampus, hypothalamus,
and olfactory bulb of the mouse brain was investigated using nanoflow ultrahigh pressure …

Environmental enrichment ameliorates high-fat diet induced olfactory deficit and decrease of parvalbumin neurons in the olfactory bulb in mice

GJ Zou, JZ Su, ZQ Jiang, KZ Chen, ZH Zeng… - Brain Research …, 2022 - Elsevier
… Overweight induced by high-fat diet (HFD) represents one of … of high-fat diet on olfaction
and organization of olfactory bulb … poorer odor sensitivity and olfactory memory relative to …

The olfactory bulb: a metabolic sensor of brain insulin and glucose concentrations via a voltage-gated potassium channel

K Tucker, MA Cavallin, P Jean-Baptiste, KC Biju… - Sensory and Metabolic …, 2010 - Springer
… Maintenance on a moderately high-fat diet reduces the number of olfactory sensory neurons
… properties in a slice configuration of the olfactory bulb. A variant in the promoter of the Kv1.3 …

Reduced olfactory bulb volume in obesity and its relation to metabolic health status

M Poessel, N Breuer, A Joshi, A Pampel… - Frontiers in human …, 2020 - frontiersin.org
… Those individuals are characterized by preserved insulin sensitivity and beta cell function,
better cardiorespiratory fitness and lower visceral fat. In this respect, we believe that the …

Diet‐induced obesity resistance of Kv1. 3−/− mice is olfactory bulb dependent

K Tucker, JM Overton, DA Fadool - Journal of …, 2012 - Wiley Online Library
… chow diet or a 32% moderately high-fat diet (MHF). Caloric … At the end of 26 weeks of diet
treatment, fat pad weight and … to resistance to DIO are olfactory bulb dependent. Thus, these …

Diet-induced obesity disrupts trace element homeostasis and gene expression in the olfactory bulb

MS Totten, DM Pierce, KM Erikson - Nutrients, 2020 - mdpi.com
olfactory bulb and to identify potential interaction effects between diet, sex, and strain. Our
study is based on evidence that obesity and olfactory bulb … a low-fat diet or a high-fat diet for 16 …

Mitral cells of the olfactory bulb perform metabolic sensing and are disrupted by obesity at the level of the Kv1. 3 ion channel

DA Fadool, K Tucker, P Pedarzani - PloS one, 2011 - journals.plos.org
high-fat diet of 32% fat for 26 weeks, Kv1.3-/- mice fail to gain weight compared to their wild-type
counterparts, and removal of the olfactory bulb via bilateral olfactory … the olfactory bulb to …

Relationship Between a High-Fat Diet, Reduced Mobility, and Trace Element Overload in the Olfactory Bulbs of C57BL/6J and DBA/2J Mice

MS Totten, JM Howell, JA Tomberlin… - Biological Trace Element …, 2024 - Springer
olfactory bulb for mice fed a high fat diet as previously reported [28]. Figure 2A shows the
relationship between olfactory bulb … Figure 2B shows the relationship between olfactory bulb

Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice

BM Chelette, AM Loeven, DN Gatlin… - The Journal of …, 2022 - Wiley Online Library
fat content (diet/exercise). Histology of the main olfactory epithelium and olfactory bulb
was performed for both experiments. [Colour figure can be viewed at wileyonlinelibrary.com] …

Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning

N Thiebaud, MC Johnson, JL Butler… - Journal of …, 2014 - Soc Neuroscience
… with a moderately high fat diet of 32% fat or when crossed to a … -term DIO by challenging
mice to high-fat diets (1) in an obesity… We find that overconsumption of fat causes structural and …