Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum

AA Escalante, AA Lal, FJ Ayala - Genetics, 1998 - academic.oup.com
genetic polymorphism at 10 Plasmodium falciparum loci that are considered potential targets
for specific antimalarial vaccines. The polymorphism … -3) are more polymorphic than those …

Excess Polymorphisms in Genes for Membrane Proteins in Plasmodium falciparum

SK Volkman, DL Hartl, DF Wirth, KM Nielsen, M Choi… - Science, 2002 - science.org
… (P = 0.09). We find no evidence for extensive regions of exceptionally high polymorphism or
of exceptionally low polymorphism, … selective sweeps that reduced genetic variation locally. …

[PDF][PDF] Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren

LE Mombo, F Ntoumi, C Bisseye, S Ossari… - American Journal of …, 2003 - academia.edu
… host genetic factors in asymptomatic malaria, a form of low-grade Plasmodium falciparum
infection … relationship between the host (human) genetic polymorphisms (glucose-6-phosphate …

Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review

…, DM Mvumbi, EO Wemakoy, P De Mol… - The Lancet Infectious …, 2021 - thelancet.com
polymorphisms of the Pfkelch13 gene in Africa before January, 2019. Following PRISMA
guidelines, 53 studies that sequenced the Pfkelch13 gene … was highly polymorphic (292 alleles, …

Selection of drug resistance-mediating Plasmodium falciparum genetic polymorphisms by seasonal malaria chemoprevention in Burkina Faso

AF Somé, I Zongo, YD Compaoré… - Antimicrobial agents …, 2014 - Am Soc Microbiol
… To characterize selection by SMC of key polymorphisms, we assessed 13 SNPs in P.
falciparum … SNP prevalence before the onset of SMC and 1 month after the third treatment in P. …

K13-propeller gene polymorphisms in Plasmodium falciparum parasite population in malaria affected countries: a systematic review of prevalence and risk factors

M Ocan, D Akena, S Nsobya, MR Kamya, R Senono… - Malaria Journal, 2019 - Springer
… prevalence of k13 gene polymorphisms among P. falciparum parasites in malaria-affected …
terms used include, “K13-propeller gene polymorphisms”, “K13-polymorphisms”, “K13-gene

Mannose-Binding Lectin Plasma Levels and Gene Polymorphisms in Plasmodium falciparum Malaria

AJF Luty, JFJ Kun, PG Kremsner - The Journal of infectious …, 1998 - academic.oup.com
… frequency of MBL gene polymorphisms in groups of Gabonese children participating in a
prospective study of severe and mild malaria due to infection with Plasmodium falciparum. At …

Genetic polymorphisms linked to susceptibility to malaria

A Driss, JM Hibbert, NO Wilson, SA Iqbal… - Malaria journal, 2011 - Springer
… The influence of host genetics on susceptibility to Plasmodium falciparum malaria has been
extensively studied over the past twenty years. It is now clear that malaria parasites have …

Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America

IT Jovel, RE Mejía, E Banegas, R Piedade, J Alger… - Malaria journal, 2011 - Springer
… to be effective for treatment of Plasmodium falciparum and Plasmodium vivax malaria. The
aim of … associated genetic polymorphisms in P. falciparum and P. vivax collected in Honduras. …

Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria

N Mariette, C Barnadas, C Bouchier, M Tichit… - Malaria journal, 2008 - Springer
… wide evaluation of genetic polymorphism for the P. falciparum and P. vivax antigens detected
by RDTs for malaria, these two species being the principal species of Plasmodium species …