Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials
M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… (erlotinib OR gefitinib) AND (controlled AND clinical trial). We selected all randomized studies
of erlotinib or gefitinib … The following study selection criteria were used: phase II and phase …
of erlotinib or gefitinib … The following study selection criteria were used: phase II and phase …
[HTML][HTML] A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations
JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… trial results for erlotinib and gefitinib led to differences in regulatory policy, no head-to-head
randomised controlled trials … initiated a randomised controlled trial of erlotinib vs gefitinib in …
randomised controlled trials … initiated a randomised controlled trial of erlotinib vs gefitinib in …
[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …
… of EGFR TKIs; instead, we have included only randomized controlled trials that compared
EGFR … This is because randomized controlled trials have a more stringent and consistent study …
EGFR … This is because randomized controlled trials have a more stringent and consistent study …
Risk of interstitial lung disease with gefitinib and erlotinib in advanced non-small cell lung cancer: a systematic review and meta-analysis of clinical trials
L Shi, J Tang, L Tong, Z Liu - Lung Cancer, 2014 - Elsevier
… to assess as individual randomized clinical trials are not powered to detect a significant
relationship. Our study pooled data from 29 randomized clinical trials to overcome this limitation, …
relationship. Our study pooled data from 29 randomized clinical trials to overcome this limitation, …
Erlotinib (Tarceva): an update on the clinical trial program
RS Herbst - Seminars in oncology, 2003 - Elsevier
… , a key aim of the erlotinib clinical trial program is to investigate erlotinib in combination with
… Moreover, in contrast to erlotinib, gefitinib is recommended for use below its monotherapy …
… Moreover, in contrast to erlotinib, gefitinib is recommended for use below its monotherapy …
Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis
… As mentioned above, both randomized controlled trials and cohort studies were included
in this systematic review. The risk of bias in randomized controlled trials was assessed using …
in this systematic review. The risk of bias in randomized controlled trials was assessed using …
… versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial
MC Garassino, O Martelli, M Broggini, G Farina… - The lancet …, 2013 - thelancet.com
… We did this randomised controlled trial in 52 Italian hospitals. … randomly assigned centrally
(1:1) to receive either erlotinib … to the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. …
(1:1) to receive either erlotinib … to the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. …
[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis
W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
… Gefitinib was proven to be the better choice for advanced NSCLC, with equal antitumor …
AEs compared with erlotinib. Further large-scale, well-designed randomized controlled trials are …
AEs compared with erlotinib. Further large-scale, well-designed randomized controlled trials are …
… bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 randomized clinical trial
TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… revealed superior PFS with osimertinib compared with first-generation EGFR TKIs (erlotinib
or gefitinib), and osimertinib has become the preferred first-line therapy. Consequently, there …
or gefitinib), and osimertinib has become the preferred first-line therapy. Consequently, there …
Use of erlotinib or gefitinib as initial therapy in advanced NSCLC
GR Oxnard, VA Miller - Oncology, 2010 - search.proquest.com
… (EGFR), such as erlotinib (Tarceva) and gefitinib (Iressa), have shown … randomized controlled
trial showing a survival benefit compared with placebo, erlotinib gained US Food and Drug …
trial showing a survival benefit compared with placebo, erlotinib gained US Food and Drug …
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