[HTML][HTML] Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB …
Z Zhou, AD Kandhare, AA Kandhare… - EXCLI …, 2019 - ncbi.nlm.nih.gov
Bleomycin (BLM) is a chemotherapeutic agent which is associated with Idiopathic
pulmonary fibrosis (IPF) due to its chronic administration. Hesperidin, a bioflavonoid has …
pulmonary fibrosis (IPF) due to its chronic administration. Hesperidin, a bioflavonoid has …
Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study
P Chitra, G Saiprasad, R Manikandan, G Sudhandiran - Toxicology Letters, 2013 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating and fatal lung disorder with
high mortality rate. Unfortunately, to date the treatment for IPF remains unsatisfying and in …
high mortality rate. Unfortunately, to date the treatment for IPF remains unsatisfying and in …
Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation
W Shi, J Hao, Y Wu, C Liu, K Shimizu, R Li… - European Journal of …, 2022 - Elsevier
Pulmonary fibrosis (PF) is a chronic interstitial lung disease with unknown etiology. In the
present study, we evaluated the anti-fibrotic effects of heterophyllin B, a natural product from …
present study, we evaluated the anti-fibrotic effects of heterophyllin B, a natural product from …
[HTML][HTML] Resveratrol alleviates bleomycin-induced pulmonary fibrosis via suppressing HIF-1α and NF-κB expression
Z Wang, X Li, H Chen, L Han, X Ji, Q Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The absence of a gold standard for treating pulmonary fibrosis makes its management
challenging. We established a rat model to study the effect of resveratrol (Res) on bleomycin …
challenging. We established a rat model to study the effect of resveratrol (Res) on bleomycin …
Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice
Idiopathic pulmonary fibrosis (IPF) is a fatal growing problem, with limited therapeutic
options. Transforming growth factor beta 1 (TGF-β1) plays a critical role in many pathological …
options. Transforming growth factor beta 1 (TGF-β1) plays a critical role in many pathological …
Vincamine Ameliorates epithelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis in rats; targeting TGF-β/MAPK/Snai1 pathway
Idiopathic pulmonary fibrosis is a progressive, irreversible lung disease that leads to
respiratory failure and death. Vincamine is an indole alkaloid obtained from the leaves of …
respiratory failure and death. Vincamine is an indole alkaloid obtained from the leaves of …
Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2–Keap1 …
The mechanism involved in the enhancement of antioxidant activities and resolved
inflammation after epigallocatechin-3-gallate (EGCG) treatment during bleomycin-induced …
inflammation after epigallocatechin-3-gallate (EGCG) treatment during bleomycin-induced …
Zingerone ameliorates oxidative stress and inflammation in bleomycin-induced pulmonary fibrosis: modulation of the expression of TGF-β1 and iNOS
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease with limited treatment
options. Zingerone found in ginger (Zingiber officinale L.) has many pharmacological effects …
options. Zingerone found in ginger (Zingiber officinale L.) has many pharmacological effects …
Nicorandil ameliorates bleomycin-induced pulmonary fibrosis in rats through modulating eNOS, iNOS, TXNIP and HIF-1α levels
MO Kseibati, GSG Shehatou, MH Sharawy, AE Eladl… - Life sciences, 2020 - Elsevier
Bleomycin (BLM) is one of the most common anti-cancer drugs used to treat numerous types
of tumors. However, pulmonary toxicity is considered the most dramatic effect of BLM …
of tumors. However, pulmonary toxicity is considered the most dramatic effect of BLM …
Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways
H Tang, L Gao, J Mao, H He, J Liu, X Cai, H Lin… - Cell Stress and …, 2016 - Springer
Pulmonary fibrosis (PF) can severely disrupt lung function, leading to fatal consequences.
Salidroside is a principal active ingredient of Rhodiola rosea and has recently been reported …
Salidroside is a principal active ingredient of Rhodiola rosea and has recently been reported …