Protein quality control in the endoplasmic reticulum (ER) is an elaborate process conserved
from yeast to mammals, ensuring that only newly synthesized proteins with correct …

The endoplasmic reticulum (ER) is the entry site of newly synthesized proteins in the
secretory pathway. Nascent polypeptide chains are co-translationally N-glycosylated at Asn …

Protein quality control in the endoplasmic reticulum (ER) is an elaborate process conserved
from yeast to mammals, ensuring that only newly synthesized proteins with correct …

Secretory proteins and membrane proteins are synthesized in the endoplasmic reticulum
(ER), and only correctly folded or properly assembled proteins are sorted to the early …

The internal environment of the eukaryotic cell is divided by membranes into various
organelles, containing diverse functional subcompartments, which allow complex cellular …

Carbohydrates are ubiquitous and play an intriguing role inside the cell as well as on the
cell surface. In addition to being part of glycan structures on glycoproteins, glycolipids or …

Endoplasmic reticulum (ER) is the site where newly synthesized proteins mature undergoing
chaperoneassisted folding and post-translational modifications. All organelle and cell …

The quality control mechanism in the endoplasmic reticulum (ER) discriminates correctly
folded proteins from misfolded polypeptides and determines their fate. Terminally misfolded …

A stringent quality control process selects misfolded polypeptides generated in the
endoplasmic reticulum (ER) for ER-associated degradation (ERAD). Here we assessed the …

Endoplasmic Reticulum maintains a quality control mechanism that monitors the biogenesis
of secretory proteins. Through this mechanism, properly folded proteins are transported to …