Sex differences, endogenous sex‐hormone hormones, sex‐hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes: 性别 …

S Liu, Q Sun - Journal of diabetes, 2018 - Wiley Online Library
摘要目前在评估2 型糖尿病的临床以及病理生理发展过程时, 有关性类固醇轴的关键作用往往被
低估了, 特别是许多与心脏代谢结果相关的性别特异性的关系. 在本期Journal of Diabetes …

[HTML][HTML] Sex hormone–binding globulin and risk of type 2 diabetes in women and men

EL Ding, Y Song, JAE Manson, DJ Hunter… - … England Journal of …, 2009 - Mass Medical Soc
Background Circulating sex hormone–binding globulin levels are inversely associated with
insulin resistance, but whether these levels can predict the risk of developing type 2 …

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

JRB Perry, MN Weedon, C Langenberg… - Human molecular …, 2010 - academic.oup.com
Epidemiological studies consistently show that circulating sex hormone binding globulin
(SHBG) levels are lower in type 2 diabetes patients than non-diabetic individuals, but the …

Sex hormone-binding globulin and type 2 diabetes mellitus

TN Le, JE Nestler, JF Strauss, EP Wickham - Trends in Endocrinology & …, 2012 - cell.com
Sex hormone-binding globulin (SHBG) has emerged as one of the multiple genetic and
environmental factors that potentially contribute to the pathophysiology of type 2 diabetes …

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

EL Ding, Y Song, VS Malik, S Liu - Jama, 2006 - jamanetwork.com
ContextInconsistent data suggest that endogenous sex hormones may have a role in sex-
dependent etiologies of type 2 diabetes, such that hyperandrogenism may increase risk in …

Combined effects of sex hormone‐binding globulin and sex hormones on risk of incident type 2 diabetes: 性激素结合球蛋白与性激素联合预测2 型糖尿病的发生

J Hu, A Zhang, S Yang, Y Wang, R Goswami… - Journal of …, 2016 - Wiley Online Library
摘要背景本研究主要目的是探讨性激素结合球蛋白(sex hormone‐binding globulin, SHBG)
与性激素联合作用是否可以预测2 型糖尿病的发生. 方法本研究为一项前瞻性巢式病例对照研究 …

[HTML][HTML] Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study

A Goto, A Morita, M Goto, S Sasaki, M Miyachi… - Cardiovascular …, 2012 - Springer
Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been
implicated in the pathogenesis of type 2 diabetes and cardiovascular diseases. As fatty liver …

Steroid sex hormones, sex hormone–binding globulin, and diabetes incidence in the diabetes prevention program

KJ Mather, C Kim, CA Christophi… - The Journal of …, 2015 - academic.oup.com
Context: Steroid sex hormones and SHBG may modify metabolism and diabetes risk, with
implications for sex-specific diabetes risk and effects of prevention interventions. Objective …

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates

Q Wang, AJ Kangas, P Soininen… - International journal …, 2015 - academic.oup.com
Background: The causal role of circulating sex hormone-binding globulin (SHBG) for type 2
diabetes is controversial. Information on the relations between SHBG and new biomarkers of …

Association of Endogenous Sex Hormones With Diabetes andImpaired Fasting Glucose in Men: Multi-Ethnic Study of Atherosclerosis

LA Colangelo, P Ouyang, K Liu, P Kopp… - Diabetes …, 2009 - Am Diabetes Assoc
OBJECTIVE To assess associations of sex hormones with impaired fasting glucose (IFG)
and type 2 diabetes in men. RESEARCH DESIGN AND METHODS A total of 3,156 African …