神经元重编程治疗脊髓损伤
X Chen, H Li - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Spinal cord injury represents a devastating central nervous system injury that could impair
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
[HTML][HTML] Neuronal reprogramming in treating spinal cord injury
X Chen, H Li - Neural regeneration research, 2022 - journals.lww.com
Spinal cord injury represents a devastating central nervous system injury that could impair
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
[HTML][HTML] Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment
R Yang, J Pan, Y Wang, P Xia, M Tai… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …
[HTML][HTML] A cutting-edge strategy for spinal cord injury treatment: resident cellular transdifferentiation
YM Fang, WC Chen, WJ Zheng, YS Yang… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Spinal cord injury causes varying degrees of motor and sensory function loss. However,
there are no effective treatments for spinal cord repair following an injury. Moreover …
there are no effective treatments for spinal cord repair following an injury. Moreover …
In vivo cell fate reprogramming for spinal cord repair
Spinal cord injury (SCI) can lead to the loss of motor, sensory, or autonomic function due to
neuronal death. Unfortunately, the adult mammalian spinal cord has limited intrinsic …
neuronal death. Unfortunately, the adult mammalian spinal cord has limited intrinsic …
Therapeutical strategies for spinal cord injury and a promising autologous astrocyte-based therapy using efficient reprogramming techniques
H Yang, C Liu, CY Wang, Q Zhang, J An, L Zhang… - Molecular …, 2016 - Springer
Spinal cord injury (SCI) is a traumatic event resulting in disturbances to normal sensory,
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …
[HTML][HTML] Improving Efficiency of Direct Pro-Neural Reprogramming: Much-Needed Aid for Neuroregeneration in Spinal Cord Injury
DA Chudakova, EM Samoilova, VP Chekhonin… - Cells, 2023 - mdpi.com
Spinal cord injury (SCI) is a medical condition affecting~ 2.5–4 million people worldwide.
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
[HTML][HTML] Regeneration of Functional Neurons After Spinal Cord Injury via in situ NeuroD1-Mediated Astrocyte-to-Neuron Conversion
B Puls, Y Ding, F Zhang, M Pan, Z Lei, Z Pei… - Frontiers in cell and …, 2020 - frontiersin.org
Spinal cord injury (SCI) often leads to impaired motor and sensory functions, partially
because the injury-induced neuronal loss cannot be easily replenished through …
because the injury-induced neuronal loss cannot be easily replenished through …
[HTML][HTML] Strategies and prospects of effective neural circuits reconstruction after spinal cord injury
B Yang, F Zhang, F Cheng, L Ying, C Wang, K Shi… - Cell Death & …, 2020 - nature.com
Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
Reversion of injured adult neurons to an embryonic state by grafts of neural progenitor cells after spinal cord injury
L Cao, Y Wang, Z Huang - Neuroscience Bulletin, 2021 - Springer
Spinal cord injury (SCI) is a severe condition characterized by neurological dysfunction,
dependence, respiratory failure, psychological morbidities, and an increased mortality rate …
dependence, respiratory failure, psychological morbidities, and an increased mortality rate …